ASTRESSIN. 0.5mg The Glu30 to Lys33 lactam bridge constrains astressin in an +-helical conformation ...
ASTRESSIN. 0.5mg The Glu30 to Lys33 lactam bridge constrains astressin in an +-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than +-helical CRF (9-41) (H-2040) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date. CAS: 170809-51-5 C161H269N49O42 FW: 3563.24 . Synonym: (D-Phe12,Nle21-+38,Glu30,Lys33)-CRF (12-41) (human, rat) Read more
