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ALLM. Inhibitor of calpain I (Ki=120nM), calpain II (Ki=230nM), cathepsin B (Ki=100nM) and cathepsin L (Ki=0.6nM). Purity: single spot by TLC. Soluble in DMSO and ethanol. CAS: 110115-07-6. FW: 401.6. 25mg white solid.

Chymostatin. ( {[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal\}). White solid. Major form is A. Protease inhibitor produced by actinomycetes.

Chymostatin. ( {[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal\}). White solid. Major form is A. Protease inhibitor produced by actinomycetes.

Chymostatin. ( {[(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A = Leu; B = Val; or C = Ile]-phenylalaninal\}). White solid. Major form is A. Protease inhibitor produced by actinomycetes.

Cystatin C, Human Urine. (Post g-globulin). Lyophilized solid from 20 mM NH4HCO3. A low molecular weight non-glycosylated basic protein of the cystatin superfamily of cysteine protease inhibitors that it is freely filtered by the glomerular membrane.

1-b-D-Arabinofuranosylcytosine. (Ara-C; cytarabine; cytosine arabinoside). White solid. Anticancer, antiviral agent that is especially effective against leukemias. Induces apoptosis in human myeloid leukemia cells and in rat sympathetic neurons. Soluble in H2O. RTECS HA5425000, CAS 147-94-4, M.W.

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, DiHCl. (1,5-DNS-GGACK, 2HCl). Solid. Effective irreversible inhibitor of HeLa cell plasminogen activator, Factor Xa and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Soluble in 10 mM HCl.

3,4-Dichloroisocoumarin. A potent, irreversible inhibitor of serine proteases. Reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. Purity: 99% by elemental analysis. Soluble in DMF and DMSO. CAS: 51050-59-0. FW: 215.0. White solid, 10mg.

N[alpha]-Tosyl-Lys Chloromethyl Ketone, Hydrochloride. Inhibits trypsin-like serine proteinases. Inactivates trypsin irreversibly without affecting chymotrypsin. Purity: =95% by elemental analysis. Soluble in aqueuos solutions. CAS: 4238-41-9. FW: 369.3. Off-white solid. 250mg.

N[alpha]-Tosyl-Lys Chloromethyl Ketone, Hydrochloride. Inhibits trypsin-like serine proteinases. Inactivates trypsin irreversibly without affecting chymotrypsin. Purity: =95% by elemental analysis. Soluble in aqueuos solutions. CAS: 4238-41-9. FW: 369.3. Off-white solid. 50mg.

Na-Tosyl-Phe Chloromethyl Ketone. Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. CAS: 402-71-1. Purity: =99% by TLC. Soluble in ethanol or methanol. FW: 351.5. 250mg white solid.

D-Val-Phe-Lys Chloromethyl Ketone, DiHCl. (Plasmin inhibitor, HCl; H-D-Val-Phe-Lys CMK). Lyophilized solid. PROTECT FROM MOISTURE. Selective irreversible inhibitor of plasmin with high selectivity for plasmin over urokinase. Purity: 90% by TLC. Soluble in DMSO. M.W. 497.9.

AEBSF, HCl. ( [4-(2-Aminoethyl)benzenesulfonylfluoride, HCl]). Off-white solid. HYGROSCOPIC. Specific irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No.

AEBSF, HCl. ( [4-(2-Aminoethyl)benzenesulfonylfluoride, HCl]). Off-white solid. HYGROSCOPIC. Specific irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No.

AEBSF, HCl. ( [4-(2-Aminoethyl)benzenesulfonylfluoride, HCl]). Off-white solid. HYGROSCOPIC. Specific irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No.

AEBSF, HCl. ( [4-(2-Aminoethyl)benzenesulfonylfluoride, HCl]). Off-white solid. HYGROSCOPIC. Specific irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No.

Benzamidine, HCl. White solid. Inhibitor of trypsin and trypsin-like enzymes. Inhibits Factor VII autoactivation. Purity: = 97% by titration. Soluble in H2O. RTECS CV6260000, CAS 1670-14-0, M.W. 156.6.

Benzamidine, HCl. White solid. Inhibitor of trypsin and trypsin-like enzymes. Inhibits Factor VII autoactivation. Purity: = 97% by titration. Soluble in H2O. RTECS CV6260000, CAS 1670-14-0, M.W. 156.6.

5-Bromo-2'-deoxyuridine. 5-Bromo-2''-deoxyuridine. (5-BrdU). White solid. Thymidine analog. Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Purity: = 98% by HPLC. Soluble in DMSO and 100 mM NaOH. RTECS YU7350000, CAS 59-14-3, M.W. 307.1.

CA-074. 1mg. Cathepsin B Inhibitor III. L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline. Colorless solid. An epoxysuccinyl peptide that acts as a potent, irreversible, and specific inhibitor of cathepsin B. Reduces ischemia-induced neuronal death. Purity: 98% by HPLC.

CA-074 Me. 1mg. Cathepsin B Inhibitor IV.[L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester. Colorless solid. Membrane-permeable analog of CA-074 that acts as inhibitor of intracellular cathepsin B. Purity:98% by HPLC.

Paclitaxel, Semi-Synthetic. 5mg. White solid. A semi-synthetic form of Paclitaxel (VWR # 80054-638) having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants. Purity:97% by HPLC. RTECS DA8340700, CAS 33069-62-4.

Cyclophosphamide Monohydrate. A widely used antineoplastic agent that also displays immunosuppressant activity. Induces apoptotic cell death in rat thymus through Fas/Fas ligand pathway. Purity: =97% by titration. Soluble in water. CAS: 6055-19-2. FW: 279.1. White solid, 1g.

Cisplatin. 50mg. cis-Diaminedichloroplatinum. CPDC. DDP. Yellow solid. A platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Purity: =98% by HPLC. RTECS TP2450000, CAS 15663-27-1.

Carboplatin. 25mg. cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II). JM-8. Paraplatin. White solid. An analog of Cisplatin (VWR #80501-024 ) with reduced nephrotoxicity. Displays potent antitumor activity. Purity: =98% by HPLC. RTECS TP2300000, CAS 41575-94-4.

(Z-LL)2 Ketone. 5mg. 1,3-di-(N-Carboxybenzoyl-L-leucyl-L-leucyl)amino Acetone. Off-white lyophilized solid. Cysteine protease inhibitor that specifically inhibits processing of the p-Prl signal peptide w/o affecting activities of signal peptidases and other proteases. Purity: single spot by TLC.

Cathepsin L Inhibitor IV. 1mg. Off-white solid. A potent inhibitor of cathepsin L (IC50 = 1.9 nM). Also inhibits the release of Ca2+ and hydroxyproline from bone in an in vitro bone culture system and prevents bone loss in ovariectomized mice. Purity:=98% by HPLC. 1-Naphthalenesulfonyl-Ile-Trp-CHO.

LICOCHALCONE-A SYNTHETIC-10MG - 435800-10MG

LICOCHALCONE-A SYNTHETIC-50MG - 435800-50MG

ANTIPAIN DIHYDROCHLORIDE-10MG - 178223-10MG

Paclitaxel, 6a-Hydroxy-. 20 nmol. Colorless solid. A metabolite of the anticancer agent Paclitaxel (VWR No. 80054-640). Purity: =98% by HPLC. Note: 20 nmol = 17.4 ug. Soluble in DMSO. MW 869.9.

ALLN IN SOLN-5MG EA5 - 208750-5MG

Bcl-2 Binding Peptide, Cell-Permeable. 1mg. cpm-1285. Off-white lyophilized solid. Hygroscopic. Cell-permeable peptide binding to Bcl-2 with high affinity & induces apoptosis. Displays antitumor activity in cells overexpressing Bcl-2 with no effect on normal peripheral lymphocytes. Purity=95% HPLC.

Bcl-xL BH4 4-23, Human, Cell-Permeable. 1mg. Lyophilized solid. Cell-permeable peptide that prevents apoptotic cell death by directly binding to the voltage-dependent anion channel (VDAC) & blocking its activity. Leads to the inhibition of cytochrome c release. Purity =95% HPLC. MW 3825.4.

D L-SULFORAPHANE-25MG EA25 - 574215-25MG

DL-THIORPHAN-10MG - 598510-10MG

Ganciclovir. 50mg. 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine. White solid. Nucleoside analog structurally related to Acyclovir. Prodrug activated by phosphorylation. Causes irreversible cell cycle arrest at G2/M checkpoint. Purity=98% HPLC. CAS 82410-32-0.

HISTONE DEACETYLASE INHIBITOR - 382149-1MG

Metastin (45-54). 1mg. KiSS-1 (112-121). Kisspeptin-10. Lyophilized solid. Pentadecapeptide with C-terminally amidated LRF-motif acting as selective agonist of AXOR12 and hOT7T175. Induces increase in intracellular Ca2+ levels in CHO/h175 and CHO/AXOR12:Gqi5 cells. Purity: =97% HPLC.

PIH-50MG EA250 - 528110-50MG

Penciclovir. 100mg. 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one. White solid. Carba analog of Ganciclovir (VWR #. 80512-484). Active against several herpes viruses. Induces apoptosis effectively without much genotoxicity. Purity: =98% HPLC. CAS 39809-25-1. MW253.3.

Smac-N7 Peptide, Cell-Permeable. 1mg. White lyophilized solid. The Smac-N7 peptide (VWR # 80512-664) is modified to be cell permeant by linking the lysine carboxyl terminal to the arginine of Antennapedia homeodomain 16-mer peptide via a proline linker. Purity: =95% by HPLC. MW 3051.7

SMAC-N7 PEPTIDE-5MG - 567370-5MG

[6]-Gingerol, Zingiber officinale. 5mg. 1-(4'-Hydroxy-3'-methoxyphenyl)-5-hydroxy-3-decanone. Pale yellow solid. Antitumor, apoptosis-inducing compound of ginger family blocking EGF-induced cell transformation-inhibits activation of AP-1. Purity=95% HPLC. RTECS HE0757000, CAS 23513-14-6.

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control. 1mg. cpm-1285m. Off-white lyophilized solid. Hygroscopic. Cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Purity: =95% HPLC.

PROTEASOME INHIBITOR IV-5MG - 539175-5MG

G-SECRETASE XII-5MG - 565773-5MG

FPTASE RAT RECOMB. E. COLI- - 344145-100UG

(+/-) Ibuprofen. 1gm. [(+/-)-2-(4-Isobutylphenyl)-propionic Acid. White solid. Nonsteroidal anti-inflammatory drug (NSAID) acts as reversible & competitive cyclooxygenase 1 (COX-1)inhibitor. Inhibits COX-2 at higher concentrations. Purity=99% titration. RTECS MU6640000, CAS 15687-27-1. MW 206.3.

beta Secretase Inhibitor III. 500ug. Inhibitor GL189. Lyophilized solid. Hygroscopic. Substrate analog inhibitor of b-secretase (BACE) that blocks proteolytic activity (at 5mM) in membrane fractions from BACE transfected MDCK cells. Purity: =95% by HPLC. Supplied as trifluoroacetate salt. MW 963.1

Splitomicin. 5mg. 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one. Off-white solid. Cell-permeable lactone derived from beta-naphthol acs as selective inhibitor of NAD+-dependent histone deacetylase act. of Sir2 protein. Purity=95% HPLC. CAS 5690-03-9.

VALPROIC ACID SODIUM SALT-5GM - 676380-5GM

PROTEASE INHIBITOR COCKTAIL SE - 539138-1SET

MDM2 INHIBITOR-10MG - 444145-10MG

ANGIOGENESIS INHIBITOR-10MG - 175580-10MG

HONOKIOL-10MG - 384620-10MG

Pepstatin A - 516481-25MG, 25 mg

Calbiochem® Bovine Aprotinin (from Lung) - 616370-20MG, 20 mg

Calbiochem® Bovine Aprotinin (from Lung) - 616370-100MG, 100 mg

Calbiochem® Bovine Aprotinin (from Lung) - 616370-10MG, 10 mg

VEGF INHIBITOR CBO-P11-1MG - 676496-1MG

GLYCYRRHIZIN AMMONIUM SALT-5G - 356780-5GM

PROTEASE INHIBITOR COCKTAIL 1M - 539129-1ML

EDTA-Na2, Ultra-Pure Individual Protease Inhibitors. Inhibits metalloproteases.

PMSF, Phenylmethylsulfonyl Fluoride. Ultra-Pure Individual Protease Inhibitors. Inhibits serine proteases (chymotrypsin, trypsin and thrombin) and cysteine proteases (papain).

Antipain-dihydrochloride. Ultra-Pure Individual Protease Inhibitors. Inhibits papain, trypsin, and plasmin.

Aprotinin. Ultra-Pure Individual Protease Inhibitors. Inhibits serine proteases (plasmin, kalikrein, trypsin and chymotrypsin).

Bestatin, Ultra-Pure Individual Protease Inhibitors. Inhibits amino-peptidases and other exopeptidases; not carboxypeptidases.

Chymostatin. Ultra-Pure Individual Protease Inhibitors. Inhibitor of alpha, beta, gamma, and delta chymotrypsins.

Protease inhibitor E-64 F/papain, size: 5 mg.

Leupeptin. Ultra-Pure Individual Protease Inhibitors. Inhibits serine and cysteine proteases (plamin, trypsin, papain and cathepsin B).

Pepstatin. Ultra-Pure Individual Protease Inhibitors. Inhibits Aspartic proteases (pepsin, renin, cathepsin D).

AEBSF. 4-(2-Aminoethyl)-benzenesulfonyl-fluoride,hydrochloride, Ultra-Pure Individual Protease Inhibitors. Inhibitor of serine proteases (trypsin, chymotrypsin, plasmin, plasma kallikrein, and thrombin).

Phosphoramidon. Ultra-Pure Individual Protease Inhibitors. Inhibits thermolysin, collagenase and other metalloendoproteinases.

Protease Inhibitor Set. Contains eleven ready to use individual protease inhibitors for characterization of protease activity. Set contains Antipain-dihydrochloride, Aptotinin, Bestatin, Chymostatin, E-64, EDTA-Na2, Leupeptin, Pepstatin, Phosphoramidon, AEBSF, and PMSF in 100x concentration.

G-SECRETASE INHIBITOR XX-500UG. 1ML

G-SECRETASE INHIBITOR XXI-500U. 1SEKT

INSOLUTION+TRADE; TAPI-1-500UG. 10UG

APROTININ BOVINE RECOMBINT 1MG - 616371-1MG

APROTININ BOVINE RECOMBNT 25MG - 616371-25MG

APROTININ BOVINE RECOMBINT 5MG - 616371-5MG

Leupeptin, Hemisulfate, Synthetic. Size: 10mg. Peptide Sequence: Ac-Leu-Leu-arginal, hemisulfate. Form: Off-white solid. Molar mass: 475.6. Hygrocopic. Purity: /=95% by HPLC (sum of isomers). CAS number 103476-89-7. Storage -20C

Leupeptin, Hemisulfate, Synthetic. Size: 25mg. Peptide Sequence: Ac-Leu-Leu-arginal, hemisulfate. Form: Off-white solid. Molar mass: 475.6. Hygrocopic. Purity: /=95% by HPLC (sum of isomers). CAS number 103476-89-7. Storage -20C

Sulindac Sulfone 5 Mg.

Bongkrekic Acid 100 ug.

BBL V-C-N Inhibitor (Thayer and Martin). 10x2mL. Antibiotic mixture of vancomycin, colistin and nystatin, lyophilized. Dehydrated culture media.

BBL V-C-N Inhibitor (Thayer and Martin). 10x10mL. Antibiotic mixture of Vancomycin, Colistin, and Nystatin, lyophilized. Dehydrated culture media.

V-C-N-T Inhibitor (Thayer and Martin). 10x10mL. Antibiotic mixture of Vancomycin, Colistin, Nystatin, and Trimethoprim, lyophilized. Dehydrated culture media.

ALLN [Calpain inhibitor I; N-[N-(N-Acetyl-L-leucyl)-L-leucyl]-L-norleucine] (10mg). Cell permeable peptide aldehyde inhibitor of calpain I and to a lesser extent calpain II. Also inhibits other neutral cysteine proteases, cathepsin B and L and the proteosome.

IODOACETAMIDE 25GM.. Iodoacetamide, 25 g. High quality kits and reagents for convenient sample preparation that give consistent and reliable 2-D results.Effectively disrupt cells and tissues.Clean up samples from contaminants.Efficiently dialyze small sample volumes. Accurate

D-AMINO ACID OXIDASE INHIBITOR - 138000-50MG

Inhibitor Of Wnt Production-2. Off-White solid. protect from light. packaged under inert gas. purity: ���95[perCent] by HPLC.

Protease Inhibitor Cocktails - VWRVM250-1ML, 1 mL, Protease Inhibitor Cocktail, Mammalian

Contains A Mix Of Protease Inhibitors: Aebsf, E-64, Bestain, Leupeptin And Edta Disodium Dihydrate.

AEBSF PROTEOMICS GRADE 500MG - VWRVM182-500MG

Contains A Mix Of Protease Inhibitors: Aebsf, Aprotinin, E-64, Bestatin, Edta And Leupeptin.

Protease Inhibitor Cocktails - VWRVM307-1ML, 1 mL, Protease Inhibitor Cocktail, Plant

ADAMTS-5 INHIBITOR CAS#929634-33-3 10MG - A334806-10MG

ADAMTS-5 INHIBITOR CAS#929634-33-3 25MG - A334806-25MG

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