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CYCLO(-PRO-VAL). 1G Cyclo(-Pro-Val) and other Pro-containing diketopiperazines were detected in roasted coffee. The amount of these compounds increases with the intensity of roasting, they contribute to the bitterness of taste. The bitter-tasting cyclodipeptide has also been detected in other foodstuffs as cocoa, chocolate, beef, and cheese.eCyclo(-Pro-Val), which shows antifungal activity, has also been isolated from microorganisms and further natural sources. CAS: 2854-40-2 C10H16N2O2 FW: 196.25

H-D-GLU(TRP-OH)-OH. 250mg An immunomodulating dipeptide. +-D-Glu-Trp reduced adenylate cyclase activity in macrophage and thymocyte membranes. CAS: 229305-39-9 C16H19N3O5 FW: 333.34 . Synonym: H-g-D-Glu-Trp-OH, Golotimod, Bestim

H-ASP(PHE-OH)-OH. 250mg This dipeptide was isolated and identified in urine and plasma from healthy human volunteers. It has also been used in studies investigating structure-taste relationships of dipeptides. CAS: 13433-10-8 C13H16N2O5 FW: 280.28 . Synonym: H-b-Asp-Phe-OH

H-ASP(PHE-OH)-OH. 1G This dipeptide was isolated and identified in urine and plasma from healthy human volunteers. It has also been used in studies investigating structure-taste relationships of dipeptides. CAS: 13433-10-8 C13H16N2O5 FW: 280.28 . Synonym: H-b-Asp-Phe-OH

CYCLO(-ALA-GLN). 250mg CAS: 268221-76-7 C8H13N3O3 FW: 199.21

CYCLO(-ALA-GLN). 1G CAS: 268221-76-7 C8H13N3O3 FW: 199.21

CYCLO(-ALA-GLU). 250mg CAS: 16364-36-6 C8H12N2O4 FW: 200.19

CYCLO(-ALA-GLU). 1G CAS: 16364-36-6 C8H12N2O4 FW: 200.19

CYCLO(-PRO-THR). 250mg CAS: 227777-31-3 C9H14N2O3 FW: 198.22

CYCLO(-PRO-THR). 1G CAS: 227777-31-3 C9H14N2O3 FW: 198.22

H-GLU(D-GLU-OH)-OH. 250mg C10H16N2O7 FW: 276.25 . Synonym: H-g-Glu-D-Glu-OH

H-GLU(D-GLU-OH)-OH. 1G C10H16N2O7 FW: 276.25 . Synonym: H-g-Glu-D-Glu-OH

H-PRO-THR-GLU-PHE-P-NITRO-PHE-ARG-. 5mg The p-nitrophenylalanine-containing substrate PTEF-Nph-RL has been developed for a convenient assay of pepsin and other aspartic proteinases of animal and microbial origin. It is soluble over a wide pH range, with the Km values showing only little variation (Km = 80 -M at pH 3.1 and 37-C for porcine pepsin). CAS: 90331-82-1 C44H63N11O13 FW: 954.05 . pepsin substrate

H-PRO-THR-GLU-PHE-P-NITRO-PHE-ARG-. 25mg The p-nitrophenylalanine-containing substrate PTEF-Nph-RL has been developed for a convenient assay of pepsin and other aspartic proteinases of animal and microbial origin. It is soluble over a wide pH range, with the Km values showing only little variation (Km = 80 -M at pH 3.1 and 37-C for porcine pepsin). CAS: 90331-82-1 C44H63N11O13 FW: 954.05 . pepsin substrate

ACETYL-NEUROTENSIN (8-13). 5mg The truncated sequence Ac-RRPYIL is the shortest neurotensin analog with full binding and pharmacological activities. CAS: 74853-69-3 C40H66N12O9 FW: 859.04 . neurotensin

ACETYL-NEUROTENSIN (8-13). 25mg The truncated sequence Ac-RRPYIL is the shortest neurotensin analog with full binding and pharmacological activities. CAS: 74853-69-3 C40H66N12O9 FW: 859.04 . neurotensin

PERISULFAKININ. 1mg Perisulfakinin was originally isolated from the corpora cardiaca of the American cockroach, Periplaneta americana. The peptide, which shows sequence similarity to gastrin and cholecystokinin, stimulates hindgut contractions in the same species. CAS: 125131-58-0 C64H86N18O22S2 FW: 1523.63 . perisulfakinin

A-MSH (FREE ACID). 1mg CAS: 10466-28-1 C77H108N20O20S FW: 1665.89 . Synonym: Acetyl-ACTH (1-13)

A-MSH (FREE ACID). 5mg CAS: 10466-28-1 C77H108N20O20S FW: 1665.89 . Synonym: Acetyl-ACTH (1-13)

A-MSH. 5mg +-Melanotropin, also known as +-melanocyte-stimulating hormone (+-MSH), is a 13-amino acid peptide originally characterized as a neuropeptide derived from the pituitary gland. +-MSH is synthesized from pro-opiomelanocortin (POMC) by the action of specific prohormone convertases and is involved in the regulation of important physiological functions including food intake, energy homeostasis, modulation of immune responses and photoprotection. CAS: 581-05-5 C77H109N21O19S FW: 1664.91 . Synonym: Acetyl-ACTH (1-13) amide, a-Melanotropin (human)

A-MSH. 25mg +-Melanotropin, also known as +-melanocyte-stimulating hormone (+-MSH), is a 13-amino acid peptide originally characterized as a neuropeptide derived from the pituitary gland. +-MSH is synthesized from pro-opiomelanocortin (POMC) by the action of specific prohormone convertases and is involved in the regulation of important physiological functions including food intake, energy homeostasis, modulation of immune responses and photoprotection. CAS: 581-05-5 C77H109N21O19S FW: 1664.91 . Synonym: Acetyl-ACTH (1-13) amide, a-Melanotropin (human)

A-DENDROTOXIN. 0.5mg +-Dendrotoxin (+-DTX), from the venom of the Eastern green mamba, Dendroaspis angusticeps, selectively blocks voltage-gated inactivating KG channels in synaptosomes. (Disulfide bonds between Cys7 and Cys57/Cys16 and Cys40/Cys32 and Cys53) CAS: 74504-53-3 C305H472N98O84S6 FW: 7048.11 . dendrotoxin

(NLE4,D-PHE7)-A-MSH, 1mg A synthetic analog of +-MSH which shows prolonged biological activity and is 26 times more active than +-MSH in the adenylate cyclase assay. CAS: 75921-69-6 C78H111N21O19 FW: 1646.87. Synonym: Afamelanotide, NDP-MSH, Melanotan 1, CUV1647.

(NLE4,D-PHE7)-A-MSH, 5mg A synthetic analog of +-MSH which shows prolonged biological activity and is 26 times more active than +-MSH in the adenylate cyclase assay. CAS: 75921-69-6 C78H111N21O19 FW: 1646.87. Synonym: Afamelanotide, NDP-MSH, Melanotan 1, CUV1647.

ACETYL-B-ENDORPHIN (HUMAN). 1mg CAS: 80102-04-1 C160H253N39O47S FW: 3507.07 . endorphin

ACETYL-B-ENDORPHIN (HUMAN). 5mg CAS: 80102-04-1 C160H253N39O47S FW: 3507.07 . endorphin

N1-GLUTATHIONYL-SPERMIDINE DISULF. 5mg The enzyme trypanothione reductase from the insect trypanosomatid Crithidia fasciculata not only uses trypanothione as a substrate, but also this related acyclic disulfide (Km = 149 -M). CAS: 108081-77-2 C34H66N12O10S2 FW: 867.1 . glutathione

N1-GLUTATHIONYL-SPERMIDINE DISULF. 25mg The enzyme trypanothione reductase from the insect trypanosomatid Crithidia fasciculata not only uses trypanothione as a substrate, but also this related acyclic disulfide (Km = 149 -M). CAS: 108081-77-2 C34H66N12O10S2 FW: 867.1 . glutathione

ACTH (1-10). 5mg C59H78N16O16S FW: 1299.43 . ACTH

ACTH (1-13). 1mg SYSMEHFRWGKPV. CAS: 22006-64-0 C75H106N20O19S FW: 1623.86 . ACTH

ACTH (1-17). 1mg CAS: 7266-47-9 C95H145N29O23S FW: 2093.44 . ACTH

ACTH (1-17). 5mg CAS: 7266-47-9 C95H145N29O23S FW: 2093.44 . ACTH

HIV PROTEASE SUBSTRATE VI. 1mg Sensitive chromogenic substrate for both the HIV-1 and HIV-2 proteases. C40H66N12O11 FW: 891.04 . HIV protease substrate

ACTH (1-24) (HUMAN, BOVINE, RAT), 1mg This truncated sequence containing the N-terminal 24 amino acids of ACTH still exhibits corticotropic activity, but it is less immunogenic than the full-length peptide hormone. ACTH 1-24 induces an increase in the circulating level of glucocorticoids. CAS: 16960-16-0 C136H210N40O31S FW: 2933.48. Synonym: Cosyntropin, Tetracosactide, Tetracosactrin.

ACTH (1-24) (HUMAN, BOVINE, RAT), 5mg This truncated sequence containing the N-terminal 24 amino acids of ACTH still exhibits corticotropic activity, but it is less immunogenic than the full-length peptide hormone. ACTH 1-24 induces an increase in the circulating level of glucocorticoids. CAS: 16960-16-0 C136H210N40O31S FW: 2933.48. Synonym: Cosyntropin, Tetracosactide, Tetracosactrin.

H-ARG-GLY-ASP-SER-OH. 25mg RGDS, a tetrapeptide which supports fibroblast attachment and inhibits fibronectin binding to platelets. RGDS is a target sequence for syphilis spirochete cytadherence. CAS: 91037-65-9 C15H27N7O8 FW: 433.42 . Synonym: RGDS

H-ARG-GLY-ASP-SER-OH. 100mg RGDS, a tetrapeptide which supports fibroblast attachment and inhibits fibronectin binding to platelets. RGDS is a target sequence for syphilis spirochete cytadherence. CAS: 91037-65-9 C15H27N7O8 FW: 433.42 . Synonym: RGDS

AC-SER-ASP-LYS-PRO-OH. 5mg This bioactive tetrapeptide corresponding to the N-terminus of Thymosin +G, is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP has been shown to reduce the damage to specific compartments in the bone marrow resulting from treatment with chemotherapeutic agents, ionizing radiations, hyperthermy, or phototherapy. It protects from doxorubicin-induced toxicity. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE). CAS: 127103-11-1 C20H33N5O9 FW: 487.51 . Synonym: AcSDKP, Stem Cell Proliferation Inhibitor, Goralatide, Thymosin b4 (1-4)

AC-SER-ASP-LYS-PRO-OH. 25mg This bioactive tetrapeptide corresponding to the N-terminus of Thymosin +G, is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP has been shown to reduce the damage to specific compartments in the bone marrow resulting from treatment with chemotherapeutic agents, ionizing radiations, hyperthermy, or phototherapy. It protects from doxorubicin-induced toxicity. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE). CAS: 127103-11-1 C20H33N5O9 FW: 487.51 . Synonym: AcSDKP, Stem Cell Proliferation Inhibitor, Goralatide, Thymosin b4 (1-4)

ACTH (1-39) (HUMAN). 0.5mg The major regulator of adrenal cortex function. ACTH stimulates the synthesis of steroidal hormones. CAS: 12279-41-3 C207H308N56O58S FW: 4541.13 . Synonym: Corticotropin

ACTH (1-39) (HUMAN). 1mg The major regulator of adrenal cortex function. ACTH stimulates the synthesis of steroidal hormones. CAS: 12279-41-3 C207H308N56O58S FW: 4541.13 . Synonym: Corticotropin

PACAP-27 (HUMAN, MOUSE, OVINE) 0.5mg PACAP-38 and its N-terminal fragment PACAP-27 are neuropeptides originally isolated from ovine hypothalamus, but also found in humans and rats. Both PACAP-27, which shows considerable homology with vasoactive intestinal polypeptide (VIP), and PACAP-38 stimulate adenylate cyclase much more potently than VIP. Specific PACAP receptors have been identified in different tissues and cell lines. Kojro et al. observed that the PAC1 agonists PACAP-27 and PACAP-38 strongly increased the activity of +-secretase, thus promoting the non-amyloidogenic processing of amyloid precursor protein. CAS: 127317-03-7 C142H224N40O39S FW: 3147.65. Synonym: Pituitary Adenylate Cyclase Activating Polypeptide-27 (human, mouse, ovine, porcine, rat), PACAP-38 (1-27) amide (human, mo.....

PACAP-27 (HUMAN, MOUSE, OVINE) 1mg PACAP-38 and its N-terminal fragment PACAP-27 are neuropeptides originally isolated from ovine hypothalamus, but also found in humans and rats. Both PACAP-27, which shows considerable homology with vasoactive intestinal polypeptide (VIP), and PACAP-38 stimulate adenylate cyclase much more potently than VIP. Specific PACAP receptors have been identified in different tissues and cell lines. Kojro et al. observed that the PAC1 agonists PACAP-27 and PACAP-38 strongly increased the activity of +-secretase, thus promoting the non-amyloidogenic processing of amyloid precursor protein. CAS: 127317-03-7 C142H224N40O39S FW: 3147.65. Synonym: Pituitary Adenylate Cyclase Activating Polypeptide-27 (human, mouse, ovine, porcine, rat), PACAP-38 (1-27) amide (human, mous.....

ACTH (4-10). 5mg Application of ACTH 4-10 reduced body weight in humans by enhancing energy expenditure and suppressing appetite, but it did not act in overweight persons. Long-term administration of the peptide also improved memory functions. CAS: 4037-01-8 C44H59N13O10S FW: 962.1 . Synonym: a-MSH (4-10)

ACTH (4-10). 25mg Application of ACTH 4-10 reduced body weight in humans by enhancing energy expenditure and suppressing appetite, but it did not act in overweight persons. Long-term administration of the peptide also improved memory functions. CAS: 4037-01-8 C44H59N13O10S FW: 962.1 . Synonym: a-MSH (4-10)

AMYLOID B-PROTEIN (25-35). 1mg The biologically active domain of the amyloid +-protein for neurotrophic and neurotoxic effects is located in the + (25-35) sequence GSNKGAIIGLM, which is homologous to a region in peptides of the tachykinin family.eFor an inactive control peptide see H-2964. CAS: 131602-53-4 C45H81N13O14S FW: 1060.28 . Amyloid

AMYLOID B-PROTEIN (25-35). 5mg The biologically active domain of the amyloid +-protein for neurotrophic and neurotoxic effects is located in the + (25-35) sequence GSNKGAIIGLM, which is homologous to a region in peptides of the tachykinin family.eFor an inactive control peptide see H-2964. CAS: 131602-53-4 C45H81N13O14S FW: 1060.28 . Amyloid

TACHYPLESIN I. 0.5mg Tachyplesin I is an antimicrobial peptide originally detected in the extract of hemocytes from the Japanese horseshoe crab. It inhibits the growth of both Gramnegative and -positive bacteria and forms a complex with bacterial lipopolysaccharides. These results sug gest that this peptide belongs to the family of arthropodous peptide antibiotics. Furthermore this peptide has been shown to have antiviral activity against vesicular stomatitis virus, influenza A virus and HIV-1. (Disulfide bonds between Cys3 and Cys16/Cys7 and Cys12) CAS: 118231-04-2 C99H151N35O19S4 FW: 2263.78 . tachyplesin

TACHYPLESIN I. 1mg Tachyplesin I is an antimicrobial peptide originally detected in the extract of hemocytes from the Japanese horseshoe crab. It inhibits the growth of both Gramnegative and -positive bacteria and forms a complex with bacterial lipopolysaccharides. These results sug gest that this peptide belongs to the family of arthropodous peptide antibiotics. Furthermore this peptide has been shown to have antiviral activity against vesicular stomatitis virus, influenza A virus and HIV-1. (Disulfide bonds between Cys3 and Cys16/Cys7 and Cys12) CAS: 118231-04-2 C99H151N35O19S4 FW: 2263.78 . tachyplesin

ACTH (7-38) (HUMAN). 0.5mg CAS: 68563-24-6 C167H257N47O46 FW: 3659.17 . Synonym: Corticotropin-Inhibiting Peptide (CIP)

ACTH (7-38) (HUMAN). 1mg CAS: 68563-24-6 C167H257N47O46 FW: 3659.17 . Synonym: Corticotropin-Inhibiting Peptide (CIP)

ACTH (11-24). 5mg CAS: 4237-93-8 C77H134N24O16 FW: 1652.06 . ACTH

ACTH (11-24). 25mg CAS: 4237-93-8 C77H134N24O16 FW: 1652.06 . ACTH

ACTH (18-39) (HUMAN). 1mg CAS: 53917-42-3 C112H165N27O36 FW: 2465.7 . Synonym: Corticotropin-Like Intermediate Peptide (CLIP)

ACTH (18-39) (HUMAN). 5mg CAS: 53917-42-3 C112H165N27O36 FW: 2465.7 . Synonym: Corticotropin-Like Intermediate Peptide (CLIP)

H-CYS-ASP-PRO-GLY-TYR-ILE-GLY-SER-. 1mg The peptide CDPGYIGSR amide, which comprises residues 925-933 of the laminin B1 chain, inhibited both angiogenesis and solid tumor growth. CAS: 110590-61-9 C40H63N13O13S FW: 966.09 . laminin

H-CYS-ASP-PRO-GLY-TYR-ILE-GLY-SER-. 5mg The peptide CDPGYIGSR amide, which comprises residues 925-933 of the laminin B1 chain, inhibited both angiogenesis and solid tumor growth. CAS: 110590-61-9 C40H63N13O13S FW: 966.09 . laminin

H-ALA-ALA-ALA-OH. 1G Trialanine. Substrate for dipeptidyl peptidase II (DPP II). CAS: 5874-90-8 C9H17N3O4 FW: 231.25 . Synonym: trialanine

H-ALA-ALA-ALA-OH. 5G Trialanine. Substrate for dipeptidyl peptidase II (DPP II). CAS: 5874-90-8 C9H17N3O4 FW: 231.25 . Synonym: trialanine

INDOLICIDIN. 0.5mg This cationic, tryptophan-rich peptide was purified from bovine granulocytes. Indolicidin shows potent antimicrobial activity in vitro against bacteria and fungi. It is also highly cytotoxic to T-line cells. CAS: 140896-21-5 C100H132N26O13 FW: 1906.32 . indolicidin

INDOLICIDIN. 1mg This cationic, tryptophan-rich peptide was purified from bovine granulocytes. Indolicidin shows potent antimicrobial activity in vitro against bacteria and fungi. It is also highly cytotoxic to T-line cells. CAS: 140896-21-5 C100H132N26O13 FW: 1906.32 . indolicidin

H-D-ALA-D-ALA-D-ALA-OH. 250mg Tri-D-alanine. CAS: 1114-94-9 C9H17N3O4 FW: 231.25 . tri-D-alanine

BQ-123. 1mg BQ-123 is a potent endothelin antagonist with high selectivity for the ET-A receptor subtype. CAS: 136553-81-6 C31H42N6O7 FW: 610.71 . endothelin

BQ-123. 5mg BQ-123 is a potent endothelin antagonist with high selectivity for the ET-A receptor subtype. CAS: 136553-81-6 C31H42N6O7 FW: 610.71 . endothelin

REC HIV-1 PROTEASE (AFFINITY PUR-. 0.1mg Crystallizable grade material.eIt is suitable for co-complexing with inhibitor screens. FW: . HIV protease

H-ALA-ALA-ALA-ALA-OH. 250mg Tetraalanine is a substrate for carboxypeptidase P from pig kidneys. CAS: 926-79-4 C12H22N4O5 FW: 302.33 . Synonym: Tetraalanine

H-ALA-ALA-ALA-ALA-OH. 1G Tetraalanine is a substrate for carboxypeptidase P from pig kidneys. CAS: 926-79-4 C12H22N4O5 FW: 302.33 . Synonym: Tetraalanine

(TRP63,TRP64)-C3A (63-77), 1mg This synthetic superagonist analogue of C3a exhibited the greatest biological potency of all peptides tested. It was 12-15 times more active than natural C3a. Such an optimal potency was obtained by introducing a bulky hydrophobic group such as Trp-Trp which binds more strongly to the hydrophobic site on the receptor than does the corresponding site on the natural ligand. CAS: 130154-64-2 C86H134N26O18 FW: 1820.17. C3a.

(TRP63,TRP64)-C3A (63-77), 5mg This synthetic superagonist analogue of C3a exhibited the greatest biological potency of all peptides tested. It was 12-15 times more active than natural C3a. Such an optimal potency was obtained by introducing a bulky hydrophobic group such as Trp-Trp which binds more strongly to the hydrophobic site on the receptor than does the corresponding site on the natural ligand. CAS: 130154-64-2 C86H134N26O18 FW: 1820.17. C3a.

H-D-ALA-D-ALA-D-ALA-D-ALA-OH. 250mg Tetra-D-alanine. CAS: 926-78-3 C12H22N4O5 FW: 302.33 . tetra-D-alanine

H-ALA-ALA-ALA-ALA-ALA-OH. 100mg Pentaalanine with its strong tendency to form +-sheets may serve as a model for amyloid fibrillation and interactions of small molecules with A+. CAS: 10183-34-3 C15H27N5O6 FW: 373.41 . Synonym: Pentaalanine

H-ALA-ALA-ALA-ALA-ALA-OH. 250mg Pentaalanine with its strong tendency to form +-sheets may serve as a model for amyloid fibrillation and interactions of small molecules with A+. CAS: 10183-34-4 C15H27N5O7 FW: 374.41 . Synonym: Pentaalanine

H-D-ALA-D-ALA-D-ALA-D-ALA-D-ALA-. 250mg Penta-D-alanine. CAS: 10491-09-5 C15H27N5O6 FW: 373.41 . penta-D-alanine

H-ALA-ALA-ALA-ALA-ALA-ALA-OH. 250mg Hexaalanine. CAS: 10576-91-7 C18H32N6O7 FW: 444.49 . hexaalanine

H-ALA-ALA-ALA-ALA-ALA-ALA-OH. 1G Hexaalanine. CAS: 10576-91-7 C18H32N6O7 FW: 444.49 . hexaalanine

DERMASEPTIN. 0.5mg Dermaseptin was originally isolated from skin extracts of the South American arboreal frog, Phyllomedusa sauvagei. The strongly basic, nonhemolytic compound is the first vertebrate peptide that shows highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. With a potentially amphiphatic +-helix structure, dermaseptin probably acts by membrane permeabilization. CAS: 136033-70-0 C152H257N43O44S2 FW: 3455.11 . dermaseptin

DERMASEPTIN. 1mg Dermaseptin was originally isolated from skin extracts of the South American arboreal frog, Phyllomedusa sauvagei. The strongly basic, nonhemolytic compound is the first vertebrate peptide that shows highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. With a potentially amphiphatic +-helix structure, dermaseptin probably acts by membrane permeabilization. CAS: 136033-70-0 C152H257N43O44S2 FW: 3455.11 . dermaseptin

C-TYPE NATRIURETIC PEPTIDE (32-53. 0.5mg (Disulfide bond) CAS: 127869-51-6 C93H157N27O28S3 FW: 2197.63 . Synonym: CNP-22 (human, porcine, rat)

C-TYPE NATRIURETIC PEPTIDE (32-53). 1mg (Disulfide bond) CAS: 127869-51-6 C93H157N27O28S3 FW: 2197.63 . Synonym: CNP-22 (human, porcine, rat)

GLUTATHIONE-MONOETHYL ESTER (RED-. 100mg Glutathione-monoethyl ester is effectively transported into many cell types including erythrocytes and converted intracellularly into glutathione. The compound may therefore be useful as a protective agent against the effects of radiation and other types of toxicity as well as in experiments on glutathione transport, metabolism, and function. CAS: 92614-59-0 C12H21N3O6S FW: 335.38 . glutathione

GLUTATHIONE-MONOETHYL ESTER (RED-. 250mg Glutathione-monoethyl ester is effectively transported into many cell types including erythrocytes and converted intracellularly into glutathione. The compound may therefore be useful as a protective agent against the effects of radiation and other types of toxicity as well as in experiments on glutathione transport, metabolism, and function. CAS: 92614-59-0 C12H21N3O6S FW: 335.38 . glutathione

H-GLY-ASP-GLY-OH. 250mg GDG. CAS: 10517-27-8 C8H13N3O6 FW: 247.21

GALANIN (1-13)-SUBSTANCE P (5-11). 0.5mg The chimaeric peptide galantide is a high-affinity ligand for galanin receptors in membranes from rat hypothalamus, hippocampus, and spinal cord. There it reversibly blocks the neuronal actions of galanin in a dose-dependent manner. The peptide also reverses the galanin-mediated inhibition of insulin release from mouse pancreatic islets. Antagonists such as galantide are therefore of potential importance both as therapeutic agents and in studies on the physiological roles of galanin. CAS: 138579-66-5 C104H151N25O16S FW: 2199.56 . Synonym: Galantide, M15

GALANIN (1-13)-SUBSTANCE P (5-11). 1mg The chimaeric peptide galantide is a high-affinity ligand for galanin receptors in membranes from rat hypothalamus, hippocampus, and spinal cord. There it reversibly blocks the neuronal actions of galanin in a dose-dependent manner. The peptide also reverses the galanin-mediated inhibition of insulin release from mouse pancreatic islets. Antagonists such as galantide are therefore of potential importance both as therapeutic agents and in studies on the physiological roles of galanin. CAS: 138579-66-5 C104H151N25O16S FW: 2199.56 . Synonym: Galantide, M15

PTH (2-38) (HUMAN). 0.5mg C194H314N58O53S2 FW: 4371.12 . pTH

GUANYLIN (RAT). 0.5mg Guanylin activates the guanylate cyclase in the intestine to stimulate the production of cGMP, which in turn causes a secretory diarrhoea. Therefore, this peptide may play a role in regulating fluid and electrolyte absorption in intestines. (Disulfide bonds between Cys4 and Cys12/Cys7 and Cys15) CAS: 144940-98-7 C60H90N16O22S4 FW: 1515.73 . guanylin

GUANYLIN (RAT). 1mg Guanylin activates the guanylate cyclase in the intestine to stimulate the production of cGMP, which in turn causes a secretory diarrhoea. Therefore, this peptide may play a role in regulating fluid and electrolyte absorption in intestines. (Disulfide bonds between Cys4 and Cys12/Cys7 and Cys15) CAS: 144940-98-7 C60H90N16O22S4 FW: 1515.73 . guanylin

C-REACTIVE PROTEIN (CRP) (174-185). 1mg CRP, an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) shows similar activity by significantly enhancing the tumoricidal activity of human monocytes and alveolar macrophages in vitro. This peptide may therefore play a role as a biological response modifier in cancer therapy. CAS: 160369-86-8 C62H93N13O16 FW: 1276.5 . Synonym: RS-83277

C-REACTIVE PROTEIN (CRP) (174-185). 5mg CRP, an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) shows similar activity by significantly enhancing the tumoricidal activity of human monocytes and alveolar macrophages in vitro. This peptide may therefore play a role as a biological response modifier in cancer therapy. CAS: 160369-86-8 C62H93N13O16 FW: 1276.5 . Synonym: RS-83277

H-GLY-ARG-GLY-ASP-SER-OH. 25mg GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation. CAS: 96426-21-0 C17H30N8O9 FW: 490.47 . Synonym: GRGDS

H-GLY-ARG-GLY-ASP-SER-OH. 100mg GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation. CAS: 96426-21-0 C17H30N8O9 FW: 490.47 . Synonym: GRGDS

GALANIN 1-13-BRADYKININ 2-9 AMIDE. 0.5mg This galanin antagonist, which binds with high specificity and affinity to galanin binding sites, has been administered to rats to test the functional consequences of the galanin receptor blockade in a spatial learning task. The results sug gest that galanin antagonists might provide a new principle in the treatment of dementia and related disorders. CAS: 142846-71-7 C107H153N27O26 FW: 2233.56 . Synonym: M35

GALANIN 1-13-BRADYKININ 2-9 AMIDE. 1mg This galanin antagonist, which binds with high specificity and affinity to galanin binding sites, has been administered to rats to test the functional consequences of the galanin receptor blockade in a spatial learning task. The results sug gest that galanin antagonists might provide a new principle in the treatment of dementia and related disorders. CAS: 142846-71-7 C107H153N27O26 FW: 2233.56 . Synonym: M35

IGF-I ANALOG. 1mg This IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Such analogs might be useful in treating abnormal cell growth. (Disulfide bond) CAS: 147819-32-7 C55H88N14O15S2 FW: 1249.52 . Synonym: JB1

GALANIN (PORCINE). 0.5mg Neuropeptide originally isolated from porcine upper small intestine. CAS: 88813-36-9 C146H213N43O40 FW: 3210.56 . galanin

GALANIN (PORCINE). 1mg Neuropeptide originally isolated from porcine upper small intestine. CAS: 88813-36-9 C146H213N43O40 FW: 3210.56 . galanin

AMYLOID B-PROTEIN (1-42). 25mg DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA, 42-residue fragment of amyloid +-protein has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. A+ 1-42 readily forms neurotoxic oligomers at physiological pH.eThe peptide has been used to detect amyloid +-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients throug h fluorescence correlation spectroscopy.eFor detailed descriptions of the preparation of A+ 1-42 monomers and protofibrils please see the paper of Jan, Hartley, and Lashuel. CAS: 107761-42-2 C203H311N55O60S FW: 4514.1 . amyloid

AMYLOID B-PROTEIN (1-42). 0.5mg DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA, 42-residue fragment of amyloid +-protein has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. A+ 1-42 readily forms neurotoxic oligomers at physiological pH.eThe peptide has been used to detect amyloid +-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients throug h fluorescence correlation spectroscopy.eFor detailed descriptions of the preparation of A+ 1-42 monomers and protofibrils please see the paper of Jan, Hartley, and Lashuel. CAS: 107761-42-2 C203H311N55O60S FW: 4514.1 . amyloid

AMYLOID B-PROTEIN (1-42). 1mg DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA, 42-residue fragment of amyloid +-protein has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. A+ 1-42 readily forms neurotoxic oligomers at physiological pH.eThe peptide has been used to detect amyloid +-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients throug h fluorescence correlation spectroscopy.eFor detailed descriptions of the preparation of A+ 1-42 monomers and protofibrils please see the paper of Jan, Hartley, and Lashuel. CAS: 107761-42-2 C203H311N55O60S FW: 4514.1 . amyloid

AMYLOID B-PROTEIN (1-42). 5mg DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA, 42-residue fragment of amyloid +-protein has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. A+ 1-42 readily forms neurotoxic oligomers at physiological pH.eThe peptide has been used to detect amyloid +-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients throug h fluorescence correlation spectroscopy.eFor detailed descriptions of the preparation of A+ 1-42 monomers and protofibrils please see the paper of Jan, Hartley, and Lashuel. CAS: 107761-42-2 C203H311N55O60S FW: 4514.1 . amyloid

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