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Coelenterazine n. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is the weakest of all coelenterazine analogs and its response time to calcium is also much slower than that of native coelenterazine.

Coelenterazine n. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is the weakest of all coelenterazine analogs and its response time to calcium is also much slower than that of native coelenterazine.

Coelenterazine ip. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is almost 50 times higher than that of the aequorin formed from native coelenterazine while its response time to calcium is much slower than the latter.

Coelenterazine ip. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is almost 50 times higher than that of the aequorin formed from native coelenterazine while its response time to calcium is much slower than the latter.

Coelenterazine ip. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is almost 50 times higher than that of the aequorin formed from native coelenterazine while its response time to calcium is much slower than the latter.

Coelenterazine fcp. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is 135 times higher than that of the aequorin formed from native coelenterazine.

Coelenterazine fcp. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is 135 times higher than that of the aequorin formed from native coelenterazine.

Coelenterazine fcp. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is 135 times higher than that of the aequorin formed from native coelenterazine.

Coelenterazine i. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is about 3% that of the aequorin formed from native coelenterazine and the response time to calcium is the slowest of all coelenterazine analogs.

Coelenterazine i. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is about 3% that of the aequorin formed from native coelenterazine and the response time to calcium is the slowest of all coelenterazine analogs.

Coelenterazine i. is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is about 3% that of the aequorin formed from native coelenterazine and the response time to calcium is the slowest of all coelenterazine analogs.

Methyl coelenterazine. has been reported to be a superior antioxidant for cells against reactive oxygen species (ROS) such as singlet oxygen and superoxide anion. The coelenterazine derivative is membrane-permeant, nontoxic and highly reactive toward ROS.

Methyl coelenterazine. has been reported to be a superior antioxidant for cells against reactive oxygen species (ROS) such as singlet oxygen and superoxide anion. The coelenterazine derivative is membrane-permeant, nontoxic and highly reactive toward ROS.

Coelenterazine Sampler Kit. For researchers wishing to screen for the appropriate coelenterazine derivatives to use, we offer this kit that contains 25ug each of the following coelenterazines: native, cp, f, fcp, h, hcp, i, ip, and n.

Colenterazine 400a. Also called DeepBlueC, is a coelenterazine derivative and substrate for Renilla luciferase. It generates an emission peak centered around 400 nm and is the preferred Rluc substrate for BRET studies because it has minimal interference with the emission of the GFP acceptor.

Colenterazine 400a. Also called DeepBlueC, is a coelenterazine derivative and substrate for Renilla luciferase. It generates an emission peak centered around 400 nm and is the preferred Rluc substrate for BRET studies because it has minimal interference with the emission of the GFP acceptor.

BAPTA,AM Ester. highly selective for Ca2+ over Mg2+ and can be used to control the level of intracellular Ca2+, 25mg

Bapta, Am Ester. bapta, am ester is relatively unstable when frequently exposed to moisture. biotium offers bapta, am ester in 20x1 mg package size which facilitates storage and handling.

BAPTA,Tetracesium Salt. highly selective for Ca2+ over Mg2+ and can be used to control the level of intracellular Ca2+, 1g

BAPTA,Tetrapotassium Salt. highly selective for Ca2+ over Mg2+ and can be used to control the level of intracellular Ca2+, 1g

BAPTA,Tetrasodium Salt. highly selective for Ca2+ over Mg2+ and can be used to control the level of intracellular Ca2+, 1g

5,5'-Dibromo BAPTA,Tetrapotassium Salt. 100mg

5,5'-Difluoro Bapta, Am Ester. the cell-permeant chelator 5,5G-difluoro-bapta has high selectivity for ca2+ over mg2+, a kd for ca2+ of -635 nm and can be used to control the level of intratracellular ca2+.

5,5'-Difluoro BAPTA,Tetrapotassium Salt. 100mg

5,5'-Dimethyl Bapta, Am Ester. the cell-permeant chelator 5,5G-dimethyl-bapta has high selectivity for ca2+ over mg2+, a kd for ca2+ of -40 nm and can be used to control the level of intratracellular ca2+.

5,5'-Dimethyl BAPTA,Tetrapotassium Salt. 100mg

Fluo-3. Pentaammonium salt is a visible light excited, high affinity Ca2+ indicator. Fluo-3 is essentially nonfluorescent without Ca2+ but the fluorescence increase 40 times on Ca2+ binding.

Fluo-3. Pentapotassium salt is a visible light excited, high affinity Ca2+ indicator. Fluo-3 is essentially nonfluorescent without Ca2+ but the fluorescence increase 40 times on Ca2+ binding.

Fluo-3. Pentasodium salt is a visible light excited, high affinity Ca2+ indicator. Fluo-3 is essentially nonfluorescent without Ca2+ but the fluorescence increase 40 times on Ca2+ binding.

Fluo-3 AM ester. Unstable when frequently exposed to moisture. Biotium offers Fluo-3 AM ester in 10x100 ug package size which facilitates storage and handling.

Fluo-3 AM ester. Cell-permeant dye, fluo-3 AM ester is a visible light excited, high affinity Ca2+ indicator.

Fluo-3 AM ester, 1mM in DMSO. Fluo-3 AM ester (50014) is supplied in a ready to use form.

Fluo-3 AM ester (20x50ug). Unstable when frequently exposed to moisture. Biotium offers Fluo-3 AM ester in 20x50 ug package size which facilitates storage and handling.

Rhod-2 triammonium salt. High affinity Ca2+ indicator. Rhod-2 is essentially nonfluorescent without Ca2+ but the fluorescence increase on Ca2+ binding.

Rhod-2 tripotassium salt. High affinity Ca2+ indicator. Rhod-2 is essentially nonfluorescent without Ca2+ but the fluorescence increase on Ca2+ binding.

Rhod-2 trisodium salt. High affinity Ca2+ indicator. Rhod-2 is essentially nonfluorescent without Ca2+ but the fluorescence increase on Ca2+ binding.

Rhod-2, AM ester (10x100ug). Rhod-2 AM ester (50024) is relatively unstable when frequently exposed to moisture.

Rhod-2 AM ester. Is cell permeable and thus can be loaded into cells via incubation. Rhod-2 AM ester itself does not bind Ca2+, but it is readily hydrolyzed to rhod-2 that binds to Ca2+

Fura-2 AM ester, 1mM in DMSO. Fura-2 AM ester (50034) is supplied in a ready to use form

Fura-2 pentammonium salt. Is widely used ratiometric UV-excitable fluorescent Ca2+ indicator. Upon calcium binding, the excitation maximum of Fura-2 undergoes a blue shift from 363 nm to 335 nm

Fura-2 pentapotassium salt. Is a widely used ratiometric UV-excitable fluorescent Ca2+ indicator. Upon calcium binding,it undergoes a blue shift from 363nm to 335nm. It can be loaded into cells via microinjection or scrape loading.

Fura-2 pentasodium salt. Is widely used ratiometric UV-excitable fluorescent Ca2+ indicator.Upon calcium binding, the excitation maximum of Fura-2 undergoes a blue shift from 363 nm to 335 nm

Fura-2 AM ester (10x100ug). Fura-2 AM ester (50034) is relatively unstable when frequently exposed to moisture. Biotium offers Fura-2 AM ester in 10x100 ug package size which facilitates storage and handling.

Fura-2 AM ester (20x50ug). Fura-2 AM ester (50034) is relatively unstable when frequently exposed to moisture. Biotium offers Fura-2 AM ester in 20x50 ug package size which facilitates storage and handling.

Fura-2 AM ester. Cell permeable and can be loaded into cells via incubation. Does not bind Ca2+,binds to Ca2+ by endogenous esterases once the dye is inside the cells.

Furaptra tetrapotassium salt (aka Mag-Fura-2). Is an excellent indicator for high Ca2+ in the range of 1 uM to 100 uM. Furaptra and Fura-2 share the same chromophore and spectral change upon binding to Ca2+

Furaptra tetrasodium salt (aka Mag-Fura-2). Is an excellent indicator for high Ca2+ in the range of 1 uM to 100 uM. Furaptra and Fura-2 share the same chromophore and spectral change upon binding to Ca2+

Furaptra AM ester (10x100ug). Furaptra AM ester (50038) is relatively unstable when frequently exposed to moisture. Biotium offers Furaptra AM ester in 10x100 ug package size which facilitates storage and handling.

Furaptra AM ester (aka Mag-Fura-2 AM ester). Is cell permeable and thus can be loaded into cells via incubation. It is readily hydrolyzed to Furaptra which binds to Ca2+ by endogenous esterases once the dye is inside the cells.

Furaptra AM ester(20x50ug). Furaptra AM ester (50038) is relatively unstable when frequently exposed to moisture. Biotium offers Furaptra AM ester in 20x50 ug package size which facilitates storage and handling.

Indo-1 pentammonium salt. Is a widely used ratiometric UV-excitable fluorescent Ca2+ indicator.The emission maximum of Indo-1 undergoes a blue shift from 475 nm to 400 nm while the excitation remains unchanged.

Indo-1 pentapotassium salt. Is a widely used ratiometric UV-excitable fluorescent Ca2+ indicator.

Indo-1 pentasodium salt. Is a widely used ratiometric UV-excitable fluorescent Ca2+ indicator.Emission maximum of Indo-1 undergoes a blue shift from 475 nm to 400 nm while the excitation remains unchanged

Indo-1 AM ester (10x100ug). Indo-1 AM ester (50044) is relatively unstable when frequently exposed to moisture. Biotium offers Indo-1 AM ester in 10x100 ug package size which facilitates storage and handling.

Indo-1 AM ester (20x50ug). Indo-1 AM ester (50044) is relatively unstable when frequently exposed to moisture. Biotium offers Indo-1 AM ester in 20x50 ug package size which facilitates storage and handling.

Indo-1 AM ester. Is cell permeable and thus can be loaded into cells via incubation, readily hydrolyzed to Indo-1 which binds to Ca2+ by endogenous esterases once the dye is inside the cells.

Nonionic detergent. Useful for solubilizing large dye molecules such as Fura-2/AM, Fluo-3/AM, Indo-1/AM and Rhod-2/AM to facilitate cell loading

A-23187 Calcium Ionophore. Rapidly equilibrates intracellular and extracellular calcium concentrations. it is commonly used for-in situ-calibrations of fluorescent calcium indicators. the ionophore allows mn2+-to enter the cells and quench intracellular fluorescence of calcium indicators

Edc. has recently been found to be very useful for fixing chelators or fluorescent ion indicators in situ, thus making it useful for post histological studies following the physiological experiments

PEN. Heavy metal chelator. It does not affect Ca++, Mg++-, Na+-or K+-concentrations.

Pluronic F-127 (59000). Is supplied in a ready to use form.

Pluronic F-127 (59000). Is supplied in a ready to use form.

4-Bromo A-23187. non-fluorescent and preferred over the blue fluorescent a-23187 for in situ calibrations of uv-excited ca2+-indicators such as indo-1 and fura-2 in order to keep background fluorescence to a minimum.

Ionomycin. Commonly used to modify intracellular calcium concentrations and to calibrate fluorescent calcium indicators. It is also known for its antipoliferative effects.

Calcium Calibration Buffer. this kit provides a range of calibration buffers from the mixing of two components with accurate calcium concentrations and is useful for the calibration of fluorescent ca2+indicators.

Coelenterazine 400A. Colenterazine 400a also called DeepBlueC is a coelenterazine derivative that serves as a substrate for Renilla luciferase (Rluc). It is the preferred Rluc substrate for BRET studies because it has minimal interference with the emission of the GFP acceptor.

Indicator Polyphosphoinositide. Polyphosphoinositide-Binding Peptide, PBP10, Rho-B-Gln-Arg-Leu-Phe-Gln-Val-Lys-Gly-Arg-Arg-OH, Purity: G95% by HPLC. 1mg

CALCITONIN (RAT). 1mg (Disulfide bond) CAS: 11118-25-5 C148H228N40O46S3 FW: 3399.88 . calcitonin

N-PROCALCITONIN (HUMAN). 0.5mg Synthetic N-procalcitonin (N-PCT) has been shown to stimulate proliferation of normal and neoplastic human osteoblasts at nanomolar concentrations. Tavares et al. have demonstrated that intracerebroventricular administration of N-PCT significantly decreased food intake and body weight gain for at least 48 h in conscious, freely moving, and unstressed rats fed ad libitum. CAS: 118277-01-3 C264H426N74O97S FW: 6220.79 . Synonym: N-Procalcitonin (human), N-PCT (human)

N-PROCALCITONIN (HUMAN). 1mg Synthetic N-procalcitonin (N-PCT) has been shown to stimulate proliferation of normal and neoplastic human osteoblasts at nanomolar concentrations. Tavares et al. have demonstrated that intracerebroventricular administration of N-PCT significantly decreased food intake and body weight gain for at least 48 h in conscious, freely moving, and unstressed rats fed ad libitum. CAS: 118277-01-3 C264H426N74O97S FW: 6220.79 . Synonym: N-Procalcitonin (human), N-PCT (human)

AIP. 1mg This non-phosphorylatable analog of autocamtide-2 (H-3218) was found to be a highly specific and potent inhibitor of calmodulin-dependent protein Kinase II (IC50= 40 nM) without affecting cyclic AMP-dependent protein kinase, protein kinase C and calmodulin-dependent protein kinase IV. CAS: 167114-91-2 C64H116N22O19 FW: 1497.76 . Synonym: AIP, (Ala9)-Autocamtide-2

CALCITONIN (8-32) (SALMON I). 0.5mg Calcitonin (8-32) (salmon I) has been been proposed as an amylin receptor antagonist which is highly selective for amylin. It reverses the inhibitory effect of amylin on glucose-induced insulin release and potentiates the insulin response to glucose in the rat perfused pancreas. CAS: 155069-90-2 C119H198N36O37 FW: 2725.1 . calcitonin