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CORTISTATIN-17 (HUMAN). 1mg This peptide with structural similarities to somatostatin binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin. Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14. Like the rat cortistatin it has an effect on sleep and wakefulness pattern in rat. It decreases the light slow wave sleep (SWS1) and increases the deep slow wave sleep (SWS2) in a dose dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms. (Disulfide bond) CAS: 189450-19-9 C96H139N27O24S3 FW: 2151.53 . cortistatin

KISSPEPTIN-54 (27-54) (HUMAN). 1mg An LRF-amide motif containing fragment of malignant melanoma metastasis-suppressor KiSS-1 which binds to human GPR54, a G-protein-coupled receptor also known as AXOR12. It shows lower agonistic potency towards AXOR12 than malignant melanoma metastasis-suppressor Kisspeptin-13 (4-13) (human) (H-5544). C149H226N42O39 FW: 3229.69 . Synonym: Malignant Melanoma Metastasis-Suppressor KiSS-1 (94-121) (human), KiSS-1 (94-121) (human), Metastin (27-54) (human)

KISSPEPTIN-13 (4-13) (HUMAN). 1mg Kisspeptin-10 (YNWNSFGLRF-amide), an LRF-amide motif-containing fragment of malignant melanoma metastasis suppressor KiSS-1, shows high agonistic potency towards the human G-protein-coupled receptor GPR54 also known as AXOR12. Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. CAS: 374675-21-5 C63H83N17O14 FW: 1302.46 . Synonym: Malignant Melanoma Metastasis-Suppressor KiSS-1 (112-121) (human), KiSS-1 (112-121) (human), Metastin (45-54) (human), Kisspeptin-14 (5-14) (human), Kisspeptin-54 (45-54) (human), Kisspentin-10

KISSPEPTIN-13 (4-13) (HUMAN). 5mg Kisspeptin-10 (YNWNSFGLRF-amide), an LRF-amide motif-containing fragment of malignant melanoma metastasis suppressor KiSS-1, shows high agonistic potency towards the human G-protein-coupled receptor GPR54 also known as AXOR12. Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. CAS: 374675-21-5 C63H83N17O14 FW: 1302.46 . Synonym: Malignant Melanoma Metastasis-Suppressor KiSS-1 (112-121) (human), KiSS-1 (112-121) (human), Metastin (45-54) (human), Kisspeptin-14 (5-14) (human), Kisspeptin-54 (45-54) (human), Kisspentin-10

STRESSCOPIN (HUMAN). 0.5mg This peptide is a specific ligand for the corticotropin-releasing hormone receptor type 2 (CRHR2). Transcripts are expressed in brain and most tissues analyzed. Intraperitoneal injections of stresscopin suppresses heat-induced edema formation in anesthetized rats. It also decreases food intake and exhibits an inhibitory effect on gastric emptying activity. This CRHR2 agonist might represent an endogenous ligand for maintaining homeostasis after stress. C195H326N56O53S2 FW: 4367.21 . Synonym: SCP (human)

STRESSCOPIN (HUMAN). 1mg This peptide is a specific ligand for the corticotropin-releasing hormone receptor type 2 (CRHR2). Transcripts are expressed in brain and most tissues analyzed. Intraperitoneal injections of stresscopin suppresses heat-induced edema formation in anesthetized rats. It also decreases food intake and exhibits an inhibitory effect on gastric emptying activity. This CRHR2 agonist might represent an endogenous ligand for maintaining homeostasis after stress. C195H326N56O53S2 FW: 4367.21 . Synonym: SCP (human)

ACETYL-(TYR1,D-ARG2)-GRF (1-29) A, 0.5mg GRF antagonist. CAS: 93942-91-7 C154H255N47O43S FW: 3485.08. Synonym: Acetyl-(Tyr1,D-Arg2)-Sermorelin.

ACETYL-(TYR1,D-ARG2)-GRF (1-29) A, 1mg GRF antagonist. CAS: 93942-91-7 C154H255N47O43S FW: 3485.08. Synonym: Acetyl-(Tyr1,D-Arg2)-Sermorelin.

HUMANIN (HUMAN). 0.5mg A polypeptide suppressing neuronal cell death induced by several familial Alzheimer's disease genes and by amyloid +-protein (1-43) (human) (H-1586). It has been shown that amyloid +-protein (1-40) and amyloid +-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer's disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid +-protein have been sug gested. CAS: 330936-69-1 C119H204N34O32S2 FW: 2687.27 . humanin

HUMANIN (HUMAN). 1mg A polypeptide suppressing neuronal cell death induced by several familial Alzheimer's disease genes and by amyloid +-protein (1-43) (human) (H-1586). It has been shown that amyloid +-protein (1-40) and amyloid +-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer's disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid +-protein have been sug gested. CAS: 330936-69-1 C119H204N34O32S2 FW: 2687.27 . humanin

(GLY14)-HUMANIN (HUMAN). 0.5mg More potent neuroprotective factor than humanin. CAS: 330936-70-4 C118H202N34O31S2 FW: 2657.25 . humanin

(GLY14)-HUMANIN (HUMAN). 1mg More potent neuroprotective factor than humanin. CAS: 330936-70-4 C118H202N34O31S2 FW: 2657.25 . humanin

REC B-DEFENSIN 1 (HUMAN). 5ug +-Defensin 1 (BD-1) (human) is a small cationic peptide originally isolated from human plasma. It exerts antimicrobial activity and is constitutively expressed in epithelia at the mucosal surface. A role for BD-1 in innate immune response has been proposed. FW: . Synonym: rec BD-1 (human), rec hBD-1, rec Defensin b-1 (human)

REC B-DEFENSIN 1 (HUMAN). 20ug +-Defensin 1 (BD-1) (human) is a small cationic peptide originally isolated from human plasma. It exerts antimicrobial activity and is constitutively expressed in epithelia at the mucosal surface. A role for BD-1 in innate immune response has been proposed. FW: . Synonym: rec BD-1 (human), rec hBD-1, rec Defensin b-1 (human)

REC B-DEFENSIN 2 (HUMAN). 5ug +-Defensin 2 (BD-2) (human), an antimicrobial peptide, is expressed throug hout the epithelia of many organs. BD-2 is inducible upon contact of keratinocytes with Gram-negative bacteria or proinflammatory cytokines such as TNF-+ and IL-1+. Elevated expression has been detected in lesional epidermal keratinocytes both in psoriasis and in the inflamed skin of mastitis. CAS: 479328-13-7 FW: . Synonym: rec BD-2 (human), rec hBD-2, rec Defensin b-2 (human), hBD-2

REC B-DEFENSIN 2 (HUMAN). 20ug +-Defensin 2 (BD-2) (human), an antimicrobial peptide, is expressed throug hout the epithelia of many organs. BD-2 is inducible upon contact of keratinocytes with Gram-negative bacteria or proinflammatory cytokines such as TNF-+ and IL-1+. Elevated expression has been detected in lesional epidermal keratinocytes both in psoriasis and in the inflamed skin of mastitis. CAS: 479328-13-7 FW: . Synonym: rec BD-2 (human), rec hBD-2, rec Defensin b-2 (human), hBD-2

SENKTIDE. 1mg Senktide (selective neurokinin B receptor peptide) is a specific agonist for the substance P N-receptor in guinea pig ileum. CAS: 106128-89-6 C40H55N7O11S FW: 841.98 . Synonym: Senktide

SENKTIDE. 5mg Senktide (selective neurokinin B receptor peptide) is a specific agonist for the substance P N-receptor in guinea pig ileum. CAS: 106128-89-6 C40H55N7O11S FW: 841.98 . Synonym: Senktide

(D-SER4,D-SER(TBU)6,AZAGLY10)-LHRH, 1mg Impurity A of the Goserelin Ph. Eur. monograph. C59H84N18O14 FW: 1269.43. Synonym: (D-Ser4)-Goserelin.

(D-SER4,D-SER(TBU)6,AZAGLY10)-LHRH, 5mg Impurity A of the Goserelin Ph. Eur. monograph. C59H84N18O14 FW: 1269.43. Synonym: (D-Ser4)-Goserelin.

PALMITOYL-CYS((RS)-2,3-DI(PALMITOYL)) 5mg The non-toxic lipopeptide Pam3CSKKKK is a highly effective adjuvant for parenteral, oral and nasal immunizations. It readily dissolves in aqueous solvents and might also be applicable for DNA immunizations. CAS: 112208-00-1 C81H156N10O13S FW: 1510.26. Synonym: Pam3Cys-Ser-Lys-Lys-Lys-Lys-OH, Pam3CSK4.

BIOTINYL-A-CGRP (MOUSE, RAT), 0.5mg (Disulfide bond) C172H276N52O54S3 FW: 4032.6. CGRP.

BIOTINYL-A-CGRP (HUMAN). 0.5mg (Disulfide bond) C173H281N53O51S3 FW: 4015.66 . CGRP

CECROPIN P1. 0.5mg Cecropin P1 (SWLSKTAKKLENSAKKRISEGIAIAIQGGPR), a homolog of insect cecropins isolated from pig intestine, was thoug ht to be the first mammalian antimicrobial peptide. Later studies showed that the peptide is produced by the intestinal parasitic nematode Ascaris suum. The 31 amino acid peptide is highly potent against Gram-negative bacteria but has a reduced activity against Gram-positive bacteria. A disruptive effect on bacterial membranes has been proposed as mechanism of antimicrobial activity. CAS: 125667-96-1 C147H253N45O43 FW: 3338.9 . cecropin

SUBSTANCE P (5-11). 5mg CAS: 51165-09-4 C41H60N10O9S FW: 869.06 . Substance P

SUBSTANCE P (5-11). 25mg CAS: 51165-09-4 C41H60N10O9S FW: 869.06 . Substance P

(D-TYR5,D-SER(TBU)6,AZAGLY10)-LHRH, 1mg Impurity F of the Goserelin Ph. Eur. monograph. C59H84N18O14 FW: 1269.43. Synonym: (D-Tyr5)-Goserelin.

(D-TYR5,D-SER(TBU)6,AZAGLY10)-LHRH, 5mg Impurity F of the Goserelin Ph. Eur. monograph. C59H84N18O14 FW: 1269.43. Synonym: (D-Tyr5)-Goserelin.

ADIPOKINETIC HORMONE (APIS MELLIFER. 1mg A peptide hormone which stimulates synthesis of 1,2-diacyl-sn-glycerols in the Manduca sexta fat body. CAS: 99886-31-4 C47H65N11O14 FW: 1008.1 . Synonym: AKH (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta)

(D-HIS2,D-SER(TBU)6,AZAGLY10)-LHRH, 1mg Impurity G of the Goserelin Ph. Eur. monograph. C59H84N18O14 FW: 1269.43. Synonym: (D-His2)-Goserelin.

(D-HIS2,D-SER(TBU)6,AZAGLY10)-LHRH, 5mg Impurity G of the Goserelin Ph. Eur. monograph. C59H84N18O14 FW: 1269.43. Synonym: (D-His2)-Goserelin.

(ALA11-+22-+28)-VIP (HUMAN MOUSE, 0.5mg. Highly selective human VPAC1 receptor agonist. It showed a 1000-fold higher efficiency in stimulating adenylate cyclase activity from VPAC1 than from VPAC2 receptors and therefore represents an effective pharmacological tool to characterize VPAC1 receptor-mediated events. CAS: 291524-04-4 C139H231N43O39S FW: 3160.7. Synonym: (Ala11-+22-+28)-Aviptadil.

(ALA11-+22-+28)-VIP (HUMAN MOUSE, 1mg. Highly selective human VPAC1 receptor agonist. It showed a 1000-fold higher efficiency in stimulating adenylate cyclase activity from VPAC1 than from VPAC2 receptors and therefore represents an effective pharmacological tool to characterize VPAC1 receptor-mediated events. CAS: 291524-04-4 C139H231N43O39S FW: 3160.7. Synonym: (Ala11-+22-+28)-Aviptadil.

THYMOPENTIN. 25mg Thymopentin, an active fragment of thymopoietin (TP), reduces endocrine and behavioral responses to experimental stress, possibly by lowering plasma TP (pTP) levels. CAS: 177966-81-3 C30H49N9O9 FW: 679.77 . Synonym: Thymopoietin (32-36) (human, mouse), TP-5, (Asp34)-Thymopoietin III (32-36) (bovine), Thymopoietin-5, Thymopoietin I/II (32-36) (bovine)

THYMOPENTIN. 100mg Thymopentin, an active fragment of thymopoietin (TP), reduces endocrine and behavioral responses to experimental stress, possibly by lowering plasma TP (pTP) levels. CAS: 177966-81-3 C30H49N9O9 FW: 679.77 . Synonym: Thymopoietin (32-36) (human, mouse), TP-5, (Asp34)-Thymopoietin III (32-36) (bovine), Thymopoietin-5, Thymopoietin I/II (32-36) (bovine)

APELIN-12 (HUMAN, BOVINE, MOUSE) 1mg Apelin-12, RPRLSHKGPMPF, is an endogenous ligand of the human orphan receptor APJ and has been shown to reduce arterial blood pressure without producing a change in the heart rate in anesthetized rats. Its vasoactive effect might be exerted by activation of endothelial nitric oxide synthase. CAS: 229961-08-4 C64H103N21O14S FW: 1422.72. Synonym: (Des-Gln1)-Apelin-13 (human, bovine, mouse, rat), Preproapelin (66-77) (human, bovine, mouse, rat), Apelin Precursor (66-77) (human, bovine, mouse, rat).

APELIN-12 (HUMAN, BOVINE, MOUSE) 5mg Apelin-12, RPRLSHKGPMPF, is an endogenous ligand of the human orphan receptor APJ and has been shown to reduce arterial blood pressure without producing a change in the heart rate in anesthetized rats. Its vasoactive effect might be exerted by activation of endothelial nitric oxide synthase. CAS: 229961-08-4 C64H103N21O14S FW: 1422.72. Synonym: (Des-Gln1)-Apelin-13 (human, bovine, mouse, rat), Preproapelin (66-77) (human, bovine, mouse, rat), Apelin Precursor (66-77) (human, bovine, mouse, rat).

CARBETOCIN. 5mg This synthetic oxytocin analog shows a prolonged effect due to an increased resistance to enzymatic cleavage.eCarbetocin is highly effective in preventing post-partum hemorrhage after vaginal delivery. (Sulfide bond between Butyryl-4-yl and Cys) CAS: 37025-55-1 C45H69N11O12S FW: 988.18 . Synonym: (Butyryl1,Tyr(Me)2)-Oxytocin, (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin

CARBETOCIN. 25mg This synthetic oxytocin analog shows a prolonged effect due to an increased resistance to enzymatic cleavage.eCarbetocin is highly effective in preventing post-partum hemorrhage after vaginal delivery. (Sulfide bond between Butyryl-4-yl and Cys) CAS: 37025-55-1 C45H69N11O12S FW: 988.18 . Synonym: (Butyryl1,Tyr(Me)2)-Oxytocin, (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin

APROTININ. 5mg Widely used serine protease inhibitor.

APROTININ. 25mg Widely used serine protease inhibitor.

(D-PHE11,HIS12)-SAUVAGINE (11-40), 1mg ASV-30, a conformationally constrained analog of sauvagine, is a highly potent and selective antagonist directed against mouse CRF receptor type 2(mCRFR2+). It has been shown to suppress agonist-induced adenylate cyclase activity in human embryonic kidney (HEK) 293 cells expressing mCRFR2+. CAS: 220673-95-0 C161H274N48O46S FW: 3650.31. Synonym: Antisauvagine-30.

RFRP-2 (RAT). 1mg RFRP-3 belongs to a family of RFamide peptides termed RFamide-related peptides (RFRPs), reported to be present in the mammalian brain. The preproprotein of rat RFRPs contains two putative peptides RFRP-1 and RFRP-3 and it could be demonstrated by K.Ukena et al., that the octadecapeptide ANMEAGTMSHFPSLPQRF represents the mature form of RFPR-3 in the rat hypothalamus. CAS: 420088-80-8 C88H134N26O25S2 FW: 2020.32 . Synonym: RFamide-Related Peptide 2 (rat), Neuropeptide VF Precursor (108-125) amide (rat)

RFRP-2 (RAT). 5mg RFRP-3 belongs to a family of RFamide peptides termed RFamide-related peptides (RFRPs), reported to be present in the mammalian brain. The preproprotein of rat RFRPs contains two putative peptides RFRP-1 and RFRP-3 and it could be demonstrated by K.Ukena et al., that the octadecapeptide ANMEAGTMSHFPSLPQRF represents the mature form of RFPR-3 in the rat hypothalamus. CAS: 420088-80-8 C88H134N26O25S2 FW: 2020.32 . Synonym: RFamide-Related Peptide 2 (rat), Neuropeptide VF Precursor (108-125) amide (rat)

H-THR-PHE-LEU-LEU-ARG-NH2. 25mg Selective agonist of PAR-1. CAS: 197794-83-5 C31H53N9O6 FW: 647.82 . Synonym: TFLLRamide, (Thr1)-TRAP-5 amide, (Thr1)-PAR-1 (1-5) amide (human)

OSTEOGENIC GROWTH PEPTIDE (10-14). 1mg This C-terminal fragment of the osteogenic growth peptide (OGP), (H-8640), showed the full spectrum of OGP-like bioactivities. It has attracted considerable interest as bone anabolic agent and hematopoietic stimulator. CAS: 105250-85-9 C24H29N5O7 FW: 499.52 . Synonym: OGP (10-14)

H-P-CHLORO-PHE-D-CYS-B-(3-PYRIDYL. 0.5mg This synthetic peptide analog of somatostatin-14 had a high affinity of 5.98 nM for the somatostatin receptor subtype 5 (sst5) (compared to 1.4 nM for somatostatin-14). Therefore, it represents the first antagonist with high affinity for sst5. (Disulfide bond) CAS: 341519-04-8 C58H69ClN12O9S2 FW: 1177.85 . somatostatin

H-P-CHLORO-PHE-D-CYS-B-(3-PYRIDYL)-. 1mg This synthetic peptide analog of somatostatin-14 had a high affinity of 5.98 nM for the somatostatin receptor subtype 5 (sst5) (compared to 1.4 nM for somatostatin-14). Therefore, it represents the first antagonist with high affinity for sst5. (Disulfide bond) CAS: 341519-04-8 C58H69ClN12O9S2 FW: 1177.85 . somatostatin

BIM-23627. 0.5mg The somatostatin antagonist BIM 23627 selectively bound with high affinity to the human somatostatin receptor subtype 2 (hsst2), but was completely inactive in stimulating intracellular calcium mobilization. The IC50 values of BIM 23627 to the five human somatostatin receptor subtypes were 2757 nM (hsst1), 6.4 nM (hsst2), 44 nM (hsst3), 423 nM (hsst4), and 86.5 nM (hsst5). (Disulfide bond) CAS: 429619-37-4 C58H69ClN12O8S2 FW: 1161.85 . BIM 23627

BIM-23627. 1mg The somatostatin antagonist BIM 23627 selectively bound with high affinity to the human somatostatin receptor subtype 2 (hsst2), but was completely inactive in stimulating intracellular calcium mobilization. The IC50 values of BIM 23627 to the five human somatostatin receptor subtypes were 2757 nM (hsst1), 6.4 nM (hsst2), 44 nM (hsst3), 423 nM (hsst4), and 86.5 nM (hsst5). (Disulfide bond) CAS: 429619-37-4 C58H69ClN12O8S2 FW: 1161.85 . BIM 23627

H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH. 5mg Arginine oligomers as heptaarginine, either alone or when conjug ated to therapeutic agents or large biopolymers, have been shown to cross readily a variety of biological membranes (e.g. lipid bilayers and epithelial tissue). The importance of the guanidinium group in transport was supported by the observation that short oligomers of arginine entered cells far more rapidly than the corresponding oligomers of either lysine, histidine, ornithine, or citrulline. CAS: 165893-48-1 C42H86N28O8 FW: 1111.33 . Synonym: Heptaarginine, H(-Arg)7-OH

H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH. 25mg Arginine oligomers as heptaarginine, either alone or when conjug ated to therapeutic agents or large biopolymers, have been shown to cross readily a variety of biological membranes (e.g. lipid bilayers and epithelial tissue). The importance of the guanidinium group in transport was supported by the observation that short oligomers of arginine entered cells far more rapidly than the corresponding oligomers of either lysine, histidine, ornithine, or citrulline. CAS: 165893-48-1 C42H86N28O8 FW: 1111.33 . Synonym: Heptaarginine, H(-Arg)7-OH

(DES-BROMO)-NEUROPEPTIDE B (1-23). 1mg (Des-Bromo)-Neuropeptide B (1-23) (human), a neuropeptide B derivative, has been shown to inhibit forskolin-induced cAMP production in CHO- cells expressing either bovine or human G-protein-coupled receptor GPR7 to a similar extent as neuropeptide B (human). The IC50 values for bovine and human GPR7 are 3.5 nM and 0.58 nM, respectively. CAS: 434897-64-0 C107H162N30O30 FW: 2348.65 . Synonym: DesBr-NPB-23 (human)

HEPCIDIN-25 (HUMAN). 0.5mg Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. It acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity. (Disulfide b....

(LEU13)-MOTILIN (HUMAN, PORCINE), 1mg (Leu--)-Motilin (human, porcine) has been shown to produce an excitory response in the chicken gastrointestinal tract with a different sensitivity from region to region. The mechanisms of action were different between the proventriculus and the intestinal segments. The motilin analog contracted the intestinal segments by direct action on the smooth muscle cells whereas in the proventriculus it caused contraction and enhancement of electrical field stimulation-induced response throug h an action on the intramural cholinergic neurons. CAS: 59530-69-7 C121H190N34O35 FW: 2681.05. motilin.

(D-ALA1)-PEPTIDE T AMIDE. 5mg Potent analog of peptide T. DAPTA showed a strong anti-HIV 1 activity in monocytes/macrophages, the peptide inhibits the entry of the virus. CAS: 106362-34-9 C35H56N10O15 FW: 856.89 . Synonym: DAPTA

(D-ALA1)-PEPTIDE T AMIDE. 25mg Potent analog of peptide T. DAPTA showed a strong anti-HIV 1 activity in monocytes/macrophages, the peptide inhibits the entry of the virus. CAS: 106362-34-9 C35H56N10O15 FW: 856.89 . Synonym: DAPTA

LECIRELIN. 5mg Lecirelin is used for the induction of ovulation in cows, mares and rabbits and for the treatment of cystic ovarian acyclia in cows. CAS: 61012-19-9 C59H84N16O12 FW: 1209.42 . Synonym: Lecirelin, (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin

SAMS PEPTIDE. 5mg Specific substrate for the sucrose-non-fermenting protein kinase (SNF1) from Saccharomyces cerevisiae and its mammalian counterpart, AMP-activated protein kinase (AMPK). CAS: 125911-68-4 C74H131N29O18S2 FW: 1779.17 . Synonym: (Ser77,Arg87-+88)-ACC-a (74-88) (dephosphorylated) (bovine, ovine), (Ser76,Arg86-+87)-ACC-a (73-87) (dephosphorylated) (E. coli, rat), (Ser77,Arg87-+88)-Acetyl-CoA Carboxylase 1 (74-88) (dephosphorylated) (bovine, ovine), (Ser76,Arg86-+87)-Acetyl-CoA Carboxylase 1 (73-87) (dephosphorylated) (E. coli, rat)

(DES-OCTANOYL)-GHRELIN (HUMAN). 0.5mg It was shown that non-acylated ghrelin does not possess the pituitaric and pancreatic endocrine activities of octanoylated ghrelin in humans. CAS: 313951-59-6 C141H235N47O41 FW: 3244.71 . ghrelin

(DES-OCTANOYL)-GHRELIN (HUMAN). 1mg It was shown that non-acylated ghrelin does not possess the pituitaric and pancreatic endocrine activities of octanoylated ghrelin in humans. CAS: 313951-59-6 C141H235N47O41 FW: 3244.71 . ghrelin

CECROPIN A (1-7)-MELITTIN A (2-9). 1mg Cecropin A (1-7)-Melittin A (2-9) amide, also referred to as CAMEL0, is a synthetic hybrid peptide that is composed of portions of the naturally occurring antibiotic peptide cecropin A and melittin. CAMEL0 shows a better antimicrobial activity than the native molecules, but lacks the hemolytic properties of melittin. Studies revealed that the range of its antimicrobial activity is not only restricted to aerobic microorganisms but also included several gram-negative and gram-positive anaerobic microorganisms. Throug h its ascertained broad spectrum of antibiotic activity, this hybrid peptide may also represent an effective substitute for ciprofloxacin in the treatment of anthrax infections. CAS: 157606-25-2 C89H152N22O15 FW: 1770.33 . Synonym: Cec....

CECROPIN A (1-7)-MELITTIN A (2-9). 5mg Cecropin A (1-7)-Melittin A (2-9) amide, also referred to as CAMEL0, is a synthetic hybrid peptide that is composed of portions of the naturally occurring antibiotic peptide cecropin A and melittin. CAMEL0 shows a better antimicrobial activity than the native molecules, but lacks the hemolytic properties of melittin. Studies revealed that the range of its antimicrobial activity is not only restricted to aerobic microorganisms but also included several gram-negative and gram-positive anaerobic microorganisms. Throug h its ascertained broad spectrum of antibiotic activity, this hybrid peptide may also represent an effective substitute for ciprofloxacin in the treatment of anthrax infections. CAS: 157606-25-2 C89H152N22O15 FW: 1770.33 . Synonym: Cecr....

HEMOKININ 1 (MOUSE, RAT), 1mg Hemokinin 1 (HK-1) is encoded by the preprotachykinin C (PPT-C) gene, which could be identified in hematopoietic cells in mouse. The undecapeptide HK-1 is a full agonist of all known three tachykinin NK1, NK2, and NK3 receptors with a remarkable selectivity for the NK1 receptor. In in vivo experiments it acts with potency similar to substance P. CAS: 208041-90-1 C61H100N22O15S FW: 1413.67. Synonym: HEK-1 (mouse, rat), HK-1 (mouse, rat).

(D-LEU7)-LHRH. 5mg CAS: 53728-75-9 C55H75N17O13 FW: 1182.31 . Synonym: (D-Leu7)-Gonadorelin

KISSPEPTIN-13 (HUMAN). 1mg An LRF-amide motif containing fragment of malignant melanoma metastasis suppressor KiSS-1. It bound with low nanomolar affinity to the rat and human G protein-coupled receptor GPR54 expressed in Chinese hamster ovary K1 cells and stimulated PIP2 hydrolysis, Ca2+ mobilization, arachidonic acid release, ERK1/2 and p38 MAP kinase phosphorylation, and stress fiber formation but inhibited cell proliferation. CAS: 374675-18-0 C78H107N21O18 FW: 1626.84 . Synonym: Malignant Melanoma Metastasis-Suppressor KiSS-1 (109-121) (human), KiSS-1 (109-121) (human), Metastin (42-54) (human), Kisspeptin-14 (2-14) (human), Kisspeptin-54 (42-54) (human)

PTH (1-34) AMIDE (HUMAN). 0.5mg CAS: 83139-29-1 C181H292N56O50S2 FW: 4116.79 . pTH

BNP-32 (RAT). 1mg (Disulfide bond) CAS: 133448-20-1 C146H239N47O44S3 FW: 3452.99 . Synonym: Brain Natriuretic Peptide-32 (rat)

OCTREOTIDE. 1mg Octreotide is a longer acting synthetic octapeptide analog of the naturally occurring hormone somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormones. Melacini et al. studied the conformation of the peptide in solution by NMR. (Disulfide bond) CAS: 79517-01-4 C49H66N10O10S2 FW: 1019.26 . Synonym: SMS 201-995, (D-Phe5,Cys6-+11,D-Trp8,L-Threoninol12)-Somatostatin-14 (5-12)

OCTREOTIDE. 5mg Octreotide is a longer acting synthetic octapeptide analog of the naturally occurring hormone somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormones. Melacini et al. studied the conformation of the peptide in solution by NMR. (Disulfide bond) CAS: 79517-01-4 C49H66N10O10S2 FW: 1019.26 . Synonym: SMS 201-995, (D-Phe5,Cys6-+11,D-Trp8,L-Threoninol12)-Somatostatin-14 (5-12)

PTH (1-37) (HUMAN). 0.5mg pTH (1-37) (human) is supposed to be the native bioactive fragment of pTH (1-84) (human) in circulation. Furthermore it was shown that pulsatile but not continuous administration of pTH (1-37) (human) increased growth, bone calcium content, and bone mineral density in uremic animals. CAS: 136799-54-7 C195H316N58O54S2 FW: 4401.15 . Synonym: Parathyroid Hormone (1-37) (human), Parathyrin (1-37) (human)

ORPHAN GPCR SP9155 AGONIST P518. 0.5mg P518 (human) is an RF-amide peptide ligand for SP9155, an orphan G-protein-coupled receptor with high homology to orexin, neuropeptide FF and CCK receptors. It has been shown to potently activate SP9155 with an EC50 of 7 nM. CAS: 600171-68-4 C127H195N37O37 FW: 2832.17 . Synonym: P518 (human), Orphan G-Protein Coupled Receptor SP9155 Agonist Peptide P518 (human)

ORPHAN GPCR SP9155 AGONIST P518. 1mg P518 (human) is an RF-amide peptide ligand for SP9155, an orphan G-protein-coupled receptor with high homology to orexin, neuropeptide FF and CCK receptors. It has been shown to potently activate SP9155 with an EC50 of 7 nM. CAS: 600171-68-4 C127H195N37O37 FW: 2832.17 . Synonym: P518 (human), Orphan G-Protein Coupled Receptor SP9155 Agonist Peptide P518 (human)

H-D-ALA-GLY-GLY-OH. 1G CAS: 77286-90-9 C7H13N3O4 FW: 203.2

PEPTIDE YY (3-36) (CANINE, MOUSE) 0.5mg Peptide YY (3-36) and peptide YY are both synthesized by the gastrointestinal tract and released into the circulation after a meal. Peptide YY (3-36) is a YG receptor subtype agonist, whereas peptide YY is non-selective for YG and YG receptor subtypes. It has been suggested that YG and YG receptor subtype binding affinities depend on their secondary and tertiary solution state structures. CAS: 126339-09-1 C176H272N52O54 FW: 3980.41. Synonym: PYY (3-36) (canine, mouse, porcine, rat).

PEPTIDE YY (3-36) (CANINE, MOUSE) 1mg Peptide YY (3-36) and peptide YY are both synthesized by the gastrointestinal tract and released into the circulation after a meal. Peptide YY (3-36) is a YG receptor subtype agonist, whereas peptide YY is non-selective for YG and YG receptor subtypes. It has been suggested that YG and YG receptor subtype binding affinities depend on their secondary and tertiary solution state structures. CAS: 126339-09-1 C176H272N52O54 FW: 3980.41. Synonym: PYY (3-36) (canine, mouse, porcine, rat).

(ALA1)-PAR-4 (1-6) AMIDE (MOUSE). 5mg This peptide based on the proteolytically-revealed tethered ligand sequence of the murine proteinase-activated receptor-4 (PAR-4) was shown to cause platelet aggregation with an EC50 value of about 15 -M. CAS: 352017-71-1 C34H48N8O7 FW: 680.8 . Synonym: (Ala1)-Proteinase Activated Receptor 4 (1-6) amide (mouse), (Ala1)-Thrombin Receptor-Like 3 (1-6) amide (mouse), (Ala1)-Coagulation Factor II Receptor-Like 3 (1-6) amide (mouse), AYPGKFamide

(ALA1)-PAR-4 (1-6) AMIDE (MOUSE). 25mg This peptide based on the proteolytically-revealed tethered ligand sequence of the murine proteinase-activated receptor-4 (PAR-4) was shown to cause platelet aggregation with an EC50 value of about 15 -M. CAS: 352017-71-1 C34H48N8O7 FW: 680.8 . Synonym: (Ala1)-Proteinase Activated Receptor 4 (1-6) amide (mouse), (Ala1)-Thrombin Receptor-Like 3 (1-6) amide (mouse), (Ala1)-Coagulation Factor II Receptor-Like 3 (1-6) amide (mouse), AYPGKFamide

H-GLY-ARG-ALA-ASP-SER-PRO-OH. 5mg GRADSP is used as negative control peptide for H-Gly-Arg-Gly-Asp-Ser-Pro-OH (H-7630). CAS: 99896-86-3 C23H39N9O10 FW: 601.62 . Synonym: GRADSP

H-GLY-ARG-ALA-ASP-SER-PRO-OH. 25mg GRADSP is used as negative control peptide for H-Gly-Arg-Gly-Asp-Ser-Pro-OH (H-7630). CAS: 99896-86-3 C23H39N9O10 FW: 601.62 . Synonym: GRADSP

ACTH (1-16). 1mg CAS: 5576-42-1 C89H133N25O22S FW: 1937.26 . ACTH

ACTH (1-16). 5mg CAS: 5576-42-1 C89H133N25O22S FW: 1937.26 . ACTH

H-P-CHLORO-PHE-D-CYS-B-(3-PYRIDYL. 0.5mg Highly potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM. Ki values for the other subtypes were 1000 nM for hsst1, 100 - 57 nM for hsst3, 895 nM for hsst4, and 520 nM for hsst5, respectively. No agonist activity was found when tested alone at concentrations up to 10 -M. In a rat pituitary growth hormone in vitro antagonist assay versus somatostatin-14 (1nM) this somatostatin octapeptide analog exhibited an IC50 value of 1.8 nM. (Disulfide bond) CAS: 209006-18-8 C59H71ClN12O8S2 FW: 1175.87 . Synonym: PRL-2915

H-P-CHLORO-PHE-D-CYS-B-(3-PYRIDYL. 1mg Highly potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM. Ki values for the other subtypes were 1000 nM for hsst1, 100 - 57 nM for hsst3, 895 nM for hsst4, and 520 nM for hsst5, respectively. No agonist activity was found when tested alone at concentrations up to 10 -M. In a rat pituitary growth hormone in vitro antagonist assay versus somatostatin-14 (1nM) this somatostatin octapeptide analog exhibited an IC50 value of 1.8 nM. (Disulfide bond) CAS: 209006-18-8 C59H71ClN12O8S2 FW: 1175.87 . Synonym: PRL-2915

INTERMEDIN (HUMAN). 0.5mg (Disulfide bond) C219H349N69O66S3 FW: 5100.8 . Synonym: hIMD, IMD (human), Adrenomedullin-2 (human), ADM2 (human)

INTERMEDIN (HUMAN). 1mg (Disulfide bond) C219H349N69O66S3 FW: 5100.8 . Synonym: hIMD, IMD (human), Adrenomedullin-2 (human), ADM2 (human)

INTERMEDIN (RAT). 0.5mg (Disulfide bond) C226H361N75O64S2 FW: 5216.95 . Synonym: rIMD, IMD (rat), Adrenomedullin-2 (rat), ADM2 (rat)

(PHE2,NLE4)-ACTH (1-24) (HUMAN) 0.5mg CAS: 97773-00-7 C137H212N40O30 FW: 2899.44. ACTH.

(PHE2,NLE4)-ACTH (1-24) (HUMAN) 1mg CAS: 97773-00-7 C137H212N40O30 FW: 2899.44. ACTH.

CHLOROTOXIN. 0.5mg (Disulfide bonds between Cys2 and Cys19/Cys5 and Cys28/Cys16 and Cys33/Cys20 and Cys35) CAS: 163515-35-3 C158H249N53O47S11 FW: 3995.77 . Synonym: Cltx (Egyptian scorpion)

CHLOROTOXIN. 1mg (Disulfide bonds between Cys2 and Cys19/Cys5 and Cys28/Cys16 and Cys33/Cys20 and Cys35) CAS: 163515-35-3 C158H249N53O47S11 FW: 3995.77 . Synonym: Cltx (Egyptian scorpion)

GASTRIC INHIBITORY POLYPEPTIDE (6. 0.5mg The porcine homolog of gastric inhibitory polypeptide (6-30) amide (human) also known as glucose-dependent insulinotropic polypeptide (6-30) amide (human) has been found to antagonize the induction of cAMP production of gastric inhibitory polypeptide (human) (GIP (human)) (H-5645) in vitro. In competitive binding studies it has been shown to exhibit receptor binding affinity equivalent to the gastric inhibitory polypeptide (human) (IC50 = 3.08 - 0.57 nM). C139H209N35O38S FW: 3010.47 . Synonym: GIP (6-30) amide (human), Glucose-Dependent Insulinotropic Polypeptide (6-30) amide (human)

GASTRIC INHIBITORY POLYPEPTIDE (6. 1mg The porcine homolog of gastric inhibitory polypeptide (6-30) amide (human) also known as glucose-dependent insulinotropic polypeptide (6-30) amide (human) has been found to antagonize the induction of cAMP production of gastric inhibitory polypeptide (human) (GIP (human)) (H-5645) in vitro. In competitive binding studies it has been shown to exhibit receptor binding affinity equivalent to the gastric inhibitory polypeptide (human) (IC50 = 3.08 - 0.57 nM). C139H209N35O38S FW: 3010.47 . Synonym: GIP (6-30) amide (human), Glucose-Dependent Insulinotropic Polypeptide (6-30) amide (human)

C-PEPTIDE 2 (RAT). 0.5mg C-Peptide 2 (rat) was shown to be effective in aug menting glucose utilization in streptozotocin diabetic rats. CAS: 41594-08-5 C135H222N38O49 FW: 3161.48 . Synonym: Insulin 2 Precursor (57-87) (rat), Preproinsulin 2 (57-87) (rat), Proinsulin 2 (33-63) (rat)

C-PEPTIDE 2 (RAT). 1mg C-Peptide 2 (rat) was shown to be effective in aug menting glucose utilization in streptozotocin diabetic rats. CAS: 41594-08-5 C135H222N38O49 FW: 3161.48 . Synonym: Insulin 2 Precursor (57-87) (rat), Preproinsulin 2 (57-87) (rat), Proinsulin 2 (33-63) (rat)

BIOTIN-EAHX-OMEGA-CONOTOXIN GVIA. 0.5mg This biotinylated --conotoxin GVIA is a useful ligand for the characterization of calcium channels. (Disulfide bonds between Cys2 and Cys17/Cys9 and Cys20/ Cys16 and Cys27) CAS: 151928-23-3 C136H207N41O46S7 FW: 3376.85 . conotoxin

BIOTIN-EAHX-OMEGA-CONOTOXIN GVIA. 1mg This biotinylated --conotoxin GVIA is a useful ligand for the characterization of calcium channels. (Disulfide bonds between Cys2 and Cys17/Cys9 and Cys20/ Cys16 and Cys27) CAS: 151928-23-3 C136H207N41O46S7 FW: 3376.85 . conotoxin

(ALA1)-PAR-4 (1-6) (MOUSE). 5mg CAS: 380900-00-5 C34H47N7O8 FW: 681.79 . Synonym: (Ala1)-Proteinase Activated Receptor 4 (1-6) (mouse), (Ala1)-Thrombin Receptor-Like 3 (1-6) (mouse), (Ala1)-Coagulation Factor II Receptor-Like 3 (1-6) (mouse), AYPGKF

(ALA1)-PAR-4 (1-6) (MOUSE). 25mg CAS: 380900-00-5 C34H47N7O8 FW: 681.79 . Synonym: (Ala1)-Proteinase Activated Receptor 4 (1-6) (mouse), (Ala1)-Thrombin Receptor-Like 3 (1-6) (mouse), (Ala1)-Coagulation Factor II Receptor-Like 3 (1-6) (mouse), AYPGKF

C-PEPTIDE 1 (RAT). 0.5mg Studies of the cellular effects of C-peptide have shown that it binds specifically in a nanomolar concentration range to a G-protein coupled membrane receptor, with subsequent activation of Ca2+-dependent intracellular signaling pathways. This resulted in stimulation of both Na+-K+-ATPase, and endothelial nitric oxide synthase activities. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover. CAS: 41475-27-8 C140H228N38O51 FW: 3259.58 . Synonym: Insulin 1 Precursor (57-87) (rat), Preproinsulin 1 (57-87) (rat), Proinsulin 1 (33-63) (rat)

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