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$

Hepcidin-24 (human). H-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH, Molecular Formula CGGGHGGGNGGOGGSG

Hepcidin-24 (human). H-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH, Molecular Formula CGGGHGGGNGGOGGSG

Endotrophin (mouse). H-Thr-Glu-Pro-Leu-Phe-Leu-Thr-Lys-Thr-Asp-Ile-Cys-Lys-Leu-Ser-Arg-Asp-Ala-Gly-Thr-Cys-Val-Asp-Phe-Lys-Leu-Leu-Trp-His-Tyr-Asp-Leu-Glu-Ser-Lys-Ser-Cys-Lys-Arg-Phe-Trp-Tyr-Gly-Gly-Cys-Gly-Gly-Asn-Glu-Asn-Arg-Phe-His-Ser-Gln-Glu-Glu-Cys-

ACETYL-HIRUDIN (54-65) (SULFATED). 1mg CAS: 125441-00-1 C68H95N13O29S FW: 1590.64 . hirudin

HIRUDIN (54-65) (DESULFATED). 1mg CAS: 113274-56-9 C66H93N13O25 FW: 1468.54 . hirudin

HIRUDIN (54-65) (DESULFATED). 5mg CAS: 113274-56-9 C66H93N13O25 FW: 1468.54 . hirudin

HIRUDIN (54-65) (SULFATED). 1mg CAS: 109528-49-6 C66H93N13O28S FW: 1548.6 . hirudin

ACETYL-HIRUDIN (55-65) (DESULFATED). 1mg CAS: 113274-57-0 C66H92N12O25 FW: 1453.52 . hirudin

ACETYL-HIRUDIN (55-65) (SULFATED). 1mg CAS: 125441-01-2 C66H92N12O28S FW: 1533.59 . hirudin

HIRUDIN (55-65) (SULFATED). 1mg CAS: 109528-50-9 C64H90N12O27S FW: 1491.55 . hirudin

TRYPANOTHIONE. 25mg Trypanothione was purified from the insect trypanosomatid Crithidia fasciculata and identified as a covalently linked adduct of glutathione and spermidine. It is utilized as a substrate by trypanothione reductase, a unique enzyme found in trypanosomes and leishmanias (Km = 51 -M). CAS: 96304-42-6 C27H47N9O10S2 FW: 721.86 . trypanothione

TRYPANOTHIONE. 100mg Trypanothione was purified from the insect trypanosomatid Crithidia fasciculata and identified as a covalently linked adduct of glutathione and spermidine. It is utilized as a substrate by trypanothione reductase, a unique enzyme found in trypanosomes and leishmanias (Km = 51 -M). CAS: 96304-42-6 C27H47N9O10S2 FW: 721.86 . trypanothione

(DES-GLY10,D-ALA6,PRO-NHET9)-LHRH, 1mg CAS: 88848-87-7 C61H76N14O12 FW: 1197.36. LHRH.

(DES-GLY10,D-ALA6,PRO-NHET9)-LHRH, 5mg CAS: 88848-87-7 C61H76N14O12 FW: 1197.36. LHRH.

REC PDGF BB (HUMAN). 2ug approx. ED50 = 1 ng/mL FW: . Synonym: Platelet-Derived Growth Factor BB

REC PDGF BB (HUMAN). 10ug approx. ED50 = 1 ng/mL FW: . Synonym: Platelet-Derived Growth Factor BB

H-GLY-ARG-GLY-ASP-SER-PRO-OH. 5mg The hexapeptide GRGDSP is used for the affinity purification of fibronectin receptors, as it contains the RGD integrin recognition site of the fibronectin cell binding domain. The immobilized peptide promotes mouse blastocyst attachment and outgrowth, whereas in solution, GRGDSP is a reversible inhibitor of entactin-mediated blastocyst outgrowth. CAS: 91037-75-1 C22H37N9O10 FW: 587.59 . Synonym: GRGDSP

H-GLY-ARG-GLY-ASP-SER-PRO-OH. 25mg The hexapeptide GRGDSP is used for the affinity purification of fibronectin receptors, as it contains the RGD integrin recognition site of the fibronectin cell binding domain. The immobilized peptide promotes mouse blastocyst attachment and outgrowth, whereas in solution, GRGDSP is a reversible inhibitor of entactin-mediated blastocyst outgrowth. CAS: 91037-75-1 C22H37N9O10 FW: 587.59 . Synonym: GRGDSP

MOTILIN (CANINE). 0.5mg A gastric motor activity-stimulating polypeptide. CAS: 85490-53-5 C120H194N36O34 FW: 2685.08 . motilin

H-GLY-ARG-GLY-ASP-THR-PRO-OH. 5mg GRGDTP prevents cell attachment of fibronectin. CAS: 108682-58-2 C23H39N9O10 FW: 601.62 . Synonym: GRGDTP

H-SER-ASP-GLY-ARG-GLY-OH. 5mg SDGRG represents a scrambled RGD peptide, the inverted sequence of H-1345. Used as control peptide for RGDS and GRGDS. CAS: 108608-63-5 C17H30N8O9 FW: 490.47 . Synonym: SDGRG

H-SER-ASP-GLY-ARG-GLY-OH. 25mg SDGRG represents a scrambled RGD peptide, the inverted sequence of H-1345. Used as control peptide for RGDS and GRGDS. CAS: 108608-63-5 C17H30N8O9 FW: 490.47 . Synonym: SDGRG

H-ARG-GLY-GLU-SER-OH. 5mg RGES, control peptide for RGDS (H-1155). CAS: 93674-97-6 C16H29N7O8 FW: 447.45 . Synonym: RGES

MAST CELL DEGRANULATING (MCD) PEP. 0.5mg The highly basic MCD peptide is present in small amounts in the venom of the European honeybee, Apis mellifera. At low doses, it causes mast cell degranulation and subsequent histamine release. At higher doses, it produces an anti-inflammatory effect, which may be beneficial in rheumatic and allergic diseases. (Disulfide bonds between Cys3 and Cys15/Cys5 and Cys19) CAS: 32908-73-9 C110H192N40O24S4 FW: 2587.25 . Synonym: Peptide 401

SARAFOTOXIN C. 0.5mg Highly selective ET-B receptor antagonist. (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) CAS: 121695-87-2 C103H147N27O37S5 FW: 2515.79 . Synonym: SRTX-C, S6C

SARAFOTOXIN C. 1mg Highly selective ET-B receptor antagonist. (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) CAS: 121695-87-2 C103H147N27O37S5 FW: 2515.79 . Synonym: SRTX-C, S6C

AC-LYS-D-ALA-D-ALA-OH. 50mg This peptide was tested as substrate in a substrate specificity study of the Streptomyces albus DD-carboxypeptidase. CAS: 28845-97-8 C14H26N4O4 FW: 330.38

DELTORPHIN I. 5mg A selective +-opioid receptor agonist isolated from the skin of Phyllomedusa bicolor. CAS: 122752-15-2 C37H52N8O10 FW: 768.87 . Synonym: Deltorphin C

DELTORPHIN I. 25mg A selective +-opioid receptor agonist isolated from the skin of Phyllomedusa bicolor. CAS: 122752-15-2 C37H52N8O10 FW: 768.87 . Synonym: Deltorphin C

DELTORPHIN II. 5mg A selective +-opioid receptor agonist isolated from the skin of Phyllomedusa bicolor. CAS: 122752-16-3 C38H54N8O10 FW: 782.9 . Synonym: Deltorphin B

DELTORPHIN II. 25mg A selective +-opioid receptor agonist isolated from the skin of Phyllomedusa bicolor. CAS: 122752-16-3 C38H54N8O10 FW: 782.9 . Synonym: Deltorphin B

TYPE A ALLATOSTATIN III. 1mg GGSLYSFGLamide, a type A allatostatin. CAS: 123338-12-5 C42H62N10O12 FW: 899.01 . allastatin

TYPE A ALLATOSTATIN III. 5mg GGSLYSFGLamide, a type A allatostatin. CAS: 123338-12-5 C42H62N10O12 FW: 899.01 . allastatin

TRAP-14. 1mg Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation. CAS: 137339-65-2 C81H118N20O23 FW: 1739.95 . Synonym: Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human), Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human), SFLLRNPNDKYEPF

TRAP-14. 5mg Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation. CAS: 137339-65-2 C81H118N20O23 FW: 1739.95 . Synonym: Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human), Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human), SFLLRNPNDKYEPF

SV40 NUCLEAR TRANSPORT SIGNAL PEP. 1mg This peptide, containing 7 amino acids homologous to the SV40 T antigen, was capable of inducing the transport of several carrier proteins to the nucleus. The terminal cysteine permits the attachment of this peptide to any protein using a heterobifunctional crosslinking reagent. Coupling to plasmid DNA has also been realized by M.G.Sebasty+n and coworkers. CAS: 104914-40-1 C60H104N20O15S FW: 1377.68 . SV40

SV40 NUCLEAR TRANSPORT SIGNAL PEP. 5mg This peptide, containing 7 amino acids homologous to the SV40 T antigen, was capable of inducing the transport of several carrier proteins to the nucleus. The terminal cysteine permits the attachment of this peptide to any protein using a heterobifunctional crosslinking reagent. Coupling to plasmid DNA has also been realized by M.G.Sebasty+n and coworkers. CAS: 104914-40-1 C60H104N20O15S FW: 1377.68 . SV40

SUCCINYL-(PRO58,D-GLU65)-HIRUDIN, 1mg This analog of the C-terminal sequence of hirudin acts as an antithrombotic agent. It inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 -M. CAS: 131791-98-5 C64H88N10O26S FW: 1445.52. hirudin.

ACETYL-HIRUDIN (53-65) (SULFATED). 1mg Hirug en, the C-terminal fragment of hirudin (residues 53-65) binds to and thereby protects thrombin against cleavage by trypsin, and to a lesser degree prevents the cleavage of thrombin by pancreatic elastase. CAS: 348603-19-0 C72H100N14O32S FW: 1705.73 . Synonym: Hirug en

O-CONOTOXIN MVIIA. 0.5mg --Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitive Ca-G channels in neurons. The peptide has been used to identify different Ca-G channel subtypes in amphibian brain. (Disulfide bonds between Cys1 and Cys16/Cys8 and Cys20/Cys15 and Cys25) CAS: 107452-89-1 C102H172N36O32S7 FW: 2639.17 . conotoxin

O-CONOTOXIN MVIIA. 1mg --Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitive Ca-G channels in neurons. The peptide has been used to identify different Ca-G channel subtypes in amphibian brain. (Disulfide bonds between Cys1 and Cys16/Cys8 and Cys20/Cys15 and Cys25) CAS: 107452-89-1 C102H172N36O32S7 FW: 2639.17 . conotoxin

(D-LYS(NICOTINOYL)1,B-(3-PYRIDYL), 1mg Spantide II is even more potent as a substance P antagonist than spantide I and less effective in releasing histamine from mast cells. Of further advantage is the negligible neurotoxicity of spantide II. CAS: 129176-97-2 C86H104Cl2N18O13 FW: 1668.79. Synonym: Spantide II.

(D-LYS(NICOTINOYL)1,B-(3-PYRIDYL), 5mg Spantide II is even more potent as a substance P antagonist than spantide I and less effective in releasing histamine from mast cells. Of further advantage is the negligible neurotoxicity of spantide II. CAS: 129176-97-2 C86H104Cl2N18O13 FW: 1668.79. Synonym: Spantide II.

TRAP-6. 5mg SFLLRN corresponds to residues 42-47 of the thrombin receptor. The hexapeptide acts as a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 -M and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+. CAS: 141136-83-6 C34H56N10O9 FW: 748.88 . Synonym: Thrombin Receptor Activator Peptide 6, PAR-1 (1-6) (human), Proteinase Activated Receptor 1 (1-6) (human), Thrombin Receptor (1-6) (human), Coagulation Factor II Receptor (1-6) (human), SFLLRN

TRAP-6. 25mg SFLLRN corresponds to residues 42-47 of the thrombin receptor. The hexapeptide acts as a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 -M and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+. CAS: 141136-83-6 C34H56N10O9 FW: 748.88 . Synonym: Thrombin Receptor Activator Peptide 6, PAR-1 (1-6) (human), Proteinase Activated Receptor 1 (1-6) (human), Thrombin Receptor (1-6) (human), Coagulation Factor II Receptor (1-6) (human), SFLLRN

AC-YVAD-CHO. 5mg Ac-YVAD-CHO is a potent, specific, reversible inhibitor of caspase-1 (ICE). It displayed a Ki of 0.2 - 0.1 nM for recombinant human caspase-1. CAS: 143313-51-3 C23H32N4O8 FW: 492.53 . Synonym: Ac-YVAD-CHO, L-709049

AC-YVAD-CHO. 25mg Ac-YVAD-CHO is a potent, specific, reversible inhibitor of caspase-1 (ICE). It displayed a Ki of 0.2 - 0.1 nM for recombinant human caspase-1. CAS: 143313-51-3 C23H32N4O8 FW: 492.53 . Synonym: Ac-YVAD-CHO, L-709049

H-GLY-LYS-GLY-OH. 250mg CAS: 45214-22-0 C10H20N4O4 FW: 260.29

H-GLY-LYS-GLY-OH. 1G CAS: 45214-22-0 C10H20N4O4 FW: 260.29

PEPTIDE YY (3-36) (HUMAN). 0.5mg PYY (3-36), a Y2 receptor agonist, is released from the body's gastrointestinal tract in proportion to caloric intake. It has been shown that peripheral injection of PYY (3-36) in rats inhibited food intake and reduced weight gain. In addition, infusion of PYY (3-36) in humans significantly decreased appetite and reduced food intake by 33% over 24h, which sug gests that PYY (3-36) has a role in 'longer term' regulation of food intake. Thus, the PYY (3-36) may represent a lead compound for the development of drug s for the treatment of obesity. CAS: 123583-37-9 C180H279N53O54 FW: 4049.52 . Synonym: PYY (3-36) (human)

PEPTIDE YY (3-36) (HUMAN). 1mg PYY (3-36), a Y2 receptor agonist, is released from the body's gastrointestinal tract in proportion to caloric intake. It has been shown that peripheral injection of PYY (3-36) in rats inhibited food intake and reduced weight gain. In addition, infusion of PYY (3-36) in humans significantly decreased appetite and reduced food intake by 33% over 24h, which sug gests that PYY (3-36) has a role in 'longer term' regulation of food intake. Thus, the PYY (3-36) may represent a lead compound for the development of drug s for the treatment of obesity. CAS: 123583-37-9 C180H279N53O54 FW: 4049.52 . Synonym: PYY (3-36) (human)

DOLASTATIN 15. 1mg Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic leukemia cell line efficiently, with an ED50 value of 2.4 ng/mL. CAS: 123884-00-4 C45H68N6O9 FW: 837.07 . dolastatin

DOLASTATIN 15. 5mg Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic leukemia cell line efficiently, with an ED50 value of 2.4 ng/mL. CAS: 123884-00-4 C45H68N6O9 FW: 837.07 . dolastatin

OSTEOSTATIN (1-5) (HUMAN. BOVINE

ACETYL-A-MSH (11-13). 50mg The acetylated C-terminal tripeptide of +-MSH shows both antipyretic and anti-inflammatory effects, althoug h to a lesser degree than +-MSH itself. CAS: 57899-96-4 C18H33N5O4 FW: 383.49 . MSH

ACETYL-A-MSH (11-13). 250mg The acetylated C-terminal tripeptide of +-MSH shows both antipyretic and anti-inflammatory effects, althoug h to a lesser degree than +-MSH itself. CAS: 57899-96-4 C18H33N5O4 FW: 383.49 . MSH

H-ASP-ASP-ASP-OH. 50mg Triaspartic acid. CAS: 107208-63-9 C12H17N3O10 FW: 363.28

H-ASP-ASP-ASP-OH. 250mg Triaspartic acid. CAS: 107208-63-9 C12H17N3O10 FW: 363.28

PAM3CYS-ALA-GLY-OH. 5mg This synthetic lipopeptide analog, corresponding to the N-terminal region of a bacterial lipoprotein, is a potent activator of macrophages. It is sug gested that the uptake of this lipopeptide into macrophages involves the aggregation of membrane proteins. CAS: 117858-54-5 C59H111N3O9S FW: 1038.61 . Synonym: Pam3Cys-Ala-Gly-OH, Pam3CAG

PAM3CYS-ALA-GLY-OH. 25mg This synthetic lipopeptide analog, corresponding to the N-terminal region of a bacterial lipoprotein, is a potent activator of macrophages. It is sug gested that the uptake of this lipopeptide into macrophages involves the aggregation of membrane proteins. CAS: 117858-54-5 C59H111N3O9S FW: 1038.61 . Synonym: Pam3Cys-Ala-Gly-OH, Pam3CAG

O-CONOTOXIN MVIIC. 0.5mg Like --conotoxin GVIA, this Conus magus peptide inhibits presynaptic Ca-G channels. However, --conotoxin MVIIC clearly inhibits additional Ca-G channel subtypes in the mammalian central nervous system. Thus, it should become a standard pharmacological reagent for investigating synaptic transmission in the mammalian nervous system. (Disulfide bonds between Cys1 and Cys16/Cys8 and Cys20/Cys15 and Cys26) CAS: 147794-23-8 C106H178N40O32S7 FW: 2749.29 . conotoxin

O-CONOTOXIN MVIIC. 1mg Like --conotoxin GVIA, this Conus magus peptide inhibits presynaptic Ca-G channels. However, --conotoxin MVIIC clearly inhibits additional Ca-G channel subtypes in the mammalian central nervous system. Thus, it should become a standard pharmacological reagent for investigating synaptic transmission in the mammalian nervous system. (Disulfide bonds between Cys1 and Cys16/Cys8 and Cys20/Cys15 and Cys26) CAS: 147794-23-8 C106H178N40O32S7 FW: 2749.29 . conotoxin

XENIN 25. 0.5mg This peptide, having 6 C-terminal amino acids in common with amphibian xenopsin, has been detected in human gastric mucosa. It stimulates the exocrine pancreatic secretion. CAS: 144092-28-4 C139H224N38O32S FW: 2971.61 . xenin

XENIN 25. 1mg This peptide, having 6 C-terminal amino acids in common with amphibian xenopsin, has been detected in human gastric mucosa. It stimulates the exocrine pancreatic secretion. CAS: 144092-28-4 C139H224N38O32S FW: 2971.61 . xenin

DEFENSIN HNP-2 (HUMAN). 0.5mg (Disulfide bonds between Cys1 and Cys29/Cys3 and Cys18/Cys8 and Cys28) CAS: 120721-97-3 C147H217N43O37S6 FW: 3371 . Synonym: Human Neutrophil Peptide-2, HNP-2

DEFENSIN HNP-2 (HUMAN). 1mg (Disulfide bonds between Cys1 and Cys29/Cys3 and Cys18/Cys8 and Cys28) CAS: 120721-97-3 C147H217N43O37S6 FW: 3371 . Synonym: Human Neutrophil Peptide-2, HNP-2

ECHISTATIN. 0.5mg Echistatin is a 49-amino acid polypeptide from the venom of the saw-scaled viper, Echis carinatus. The peptide containing an RGD motif binds to the glycoprotein IIb/IIIa receptor on the platelet and is a potent competitive inhibitor of ADPstimulated platelet aggregation mediated by fibrinogen and other factors. Furthermore, echistatin effectively inhibits osteoclastic bone resorption in vitro and in vivo. (Disulfide bonds between Cys2 and Cys11/Cys7 and Cys32/Cys8 and Cys37/Cys20 and Cys39) CAS: 154303-05-6 C217H341N71O74S9 FW: 5417.12 . echistatin

MU-CONOTOXIN GIIIB. 0.5mg This strongly basic --conotoxin from the venom of Conus geographus is highly effective in blocking sodium channels in vertebrate skeletal muscle, thereby preventing the propagation of muscle action potentials. (Disulfide bonds between Cys3 and Cys15/Cys4 and Cys20/Cys10 and Cys21) CAS: 140678-12-2 C101H175N39O30S7 FW: 2640.21 . Synonym: Geographutoxin II (GTXII)

MU-CONOTOXIN GIIIB. 1mg This strongly basic --conotoxin from the venom of Conus geographus is highly effective in blocking sodium channels in vertebrate skeletal muscle, thereby preventing the propagation of muscle action potentials. (Disulfide bonds between Cys3 and Cys15/Cys4 and Cys20/Cys10 and Cys21) CAS: 140678-12-2 C101H175N39O30S7 FW: 2640.21 . Synonym: Geographutoxin II (GTXII)

ENDOTHELIN-2 (HUMAN, CANINE), 0.5mg (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) CAS: 123562-20-9 C115H160N26O32S4 FW: 2546.96. Synonym: ET-2 (human, canine), VIC (human, canine).

ENDOTHELIN-3 (HUMAN, MOUSE, RABBIT) 0.5mg ET-1, ET-2, and ET-3 are the products of three distinct endothelin genes. ET-2 and ET-3 are similar to ET-1, but differ in two and six amino acids, respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pressor responses. However, the quantitative profiles of their pharmacological activities vary greatly. (Disulfide bonds between Cys-1and Cys15/Cys3 and Cys11) CAS: 117399-93-6 C121H168N26O33S4 FW: 2643.08. Synonym: ET-3 (human, mouse, rabbit, rat).

BIG ENDOTHELIN-1 (HUMAN). 0.5mg (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) CAS: 121014-53-7 C189H282N48O56S5 FW: 4282.94 . Synonym: Big ET-1 (1-38) (human)

LANREOTIDE. 1mg This cyclic somatostatin agonist shows a high binding affinity for the somatostatin receptor (SSTR) subtype 2 and has a 10-fold less affinity for receptor subtype 5. It is also a potent inhibitor of growth hormone secretion from pituitary cells. Furthermore, the octapeptide exhibits a direct antiproliferative effect in vivo and in vitro on the growth of cells or solid tumors from a human small cell lung carcinoma. (Disulfide bond) CAS: 108736-35-2 C54H69N11O10S2 FW: 1096.34 . Synonym: Angiopeptin, BIM-23014, DC-13-116, (D-2-Nal5,Cys6-+11,Tyr7,D-Trp8,Val10)-Somatostatin (5-12) amide

LANREOTIDE. 5mg This cyclic somatostatin agonist shows a high binding affinity for the somatostatin receptor (SSTR) subtype 2 and has a 10-fold less affinity for receptor subtype 5. It is also a potent inhibitor of growth hormone secretion from pituitary cells. Furthermore, the octapeptide exhibits a direct antiproliferative effect in vivo and in vitro on the growth of cells or solid tumors from a human small cell lung carcinoma. (Disulfide bond) CAS: 108736-35-2 C54H69N11O10S2 FW: 1096.34 . Synonym: Angiopeptin, BIM-23014, DC-13-116, (D-2-Nal5,Cys6-+11,Tyr7,D-Trp8,Val10)-Somatostatin (5-12) amide

BNP-32 (HUMAN). 0.5mg The secretion of the cardiac hormone BNP-32 is increased considerably in patients with congestive heart failure, successful medical treatment of this condition will result in a decrease. Yandle et al. described a method for determining hBNP in human plasma. Effects of hBNP infusion in man have been described by Holmes et al and La Villa et al. BNP is an important biomarker in the diagnosis of heart diseases. Additionally, BNP-32 may act as a neuropeptide.eBNP-32 exerts strong lipolytic effects in humans. (Disulfide bond) CAS: 124584-08-3 C143H244N50O42S4 FW: 3464.09 . Synonym: Brain Natriuretic Peptide-32 (human), Nesiritide

BNP-32 (HUMAN). 1mg The secretion of the cardiac hormone BNP-32 is increased considerably in patients with congestive heart failure, successful medical treatment of this condition will result in a decrease. Yandle et al. described a method for determining hBNP in human plasma. Effects of hBNP infusion in man have been described by Holmes et al and La Villa et al. BNP is an important biomarker in the diagnosis of heart diseases. Additionally, BNP-32 may act as a neuropeptide.eBNP-32 exerts strong lipolytic effects in humans. (Disulfide bond) CAS: 124584-08-3 C143H244N50O42S4 FW: 3464.09 . Synonym: Brain Natriuretic Peptide-32 (human), Nesiritide

PTH-RELATED PROTEIN (1-34) AMIDE . 0.5mg CAS: 112955-31-4 C180H288N58O47 FW: 4016.63 . Synonym: Hypercalcemia of Malignancy Factor (1-34) amide (human, mouse, rat), pTHrP (1-34) amide (human, mouse, rat)

PTH-RELATED PROTEIN (1-34) AMIDE . 1mg CAS: 112955-31-4 C180H288N58O47 FW: 4016.63 . Synonym: Hypercalcemia of Malignancy Factor (1-34) amide (human, mouse, rat), pTHrP (1-34) amide (human, mouse, rat)

PTH-RELATED PROTEIN (7-34) AMIDE . 0.5mg pTHrP (7-34) amide is a potent antagonist of the effects of pTH-related protein (1-34) in vitro and in vivo. CAS: 115695-30-2 C153H247N49O37 FW: 3364.95 . Synonym: Hypercalcemia of Malignancy Factor (7-34) amide (human, mouse, rat), pTHrP (7-34) amide (human, mouse, rat)

PTH-RELATED PROTEIN (7-34) AMIDE . 1mg pTHrP (7-34) amide is a potent antagonist of the effects of pTH-related protein (1-34) in vitro and in vivo. CAS: 115695-30-2 C153H247N49O37 FW: 3364.95 . Synonym: Hypercalcemia of Malignancy Factor (7-34) amide (human, mouse, rat), pTHrP (7-34) amide (human, mouse, rat)

(NLE8-+18,TYR34)-PTH (1-34) (HUMAN) 0.5mg CAS: 78041-34-6 C183H295N55O52 FW: 4097.69. pTH.

(NLE8-+18,TYR34)-PTH (1-34) (HUMAN) 1mg CAS: 78041-34-6 C183H295N55O52 FW: 4097.69. pTH.

(D-TRP12,TYR34)-PTH (7-34) AMIDE, 0.5mg The D-Trp12 substitution leads to a competitive pTH antagonist with increased inhibitory properties in vitro. CAS: 118102-98-0 C165H251N49O40S2 FW: 3625.25. pTH.

(D-TRP12,TYR34)-PTH (7-34) AMIDE, 1mg The D-Trp12 substitution leads to a competitive pTH antagonist with increased inhibitory properties in vitro. CAS: 118102-98-0 C165H251N49O40S2 FW: 3625.25. pTH.

FIBRINOGEN-BINDING INHIBITOR PEPTID. 5mg This synthetic dodecapeptide represents the specific platelet receptor recognition site of the human fibrinogen + chain (residues 400-411). It is a potent inhibitor of the binding of fibrinogen, fibronectin, and von Willebrand factor to thrombin- or ADP-stimulated platelets. The peptide has also been used in studying phosphorylation processes associated with platelet activation. CAS: 89105-94-2 C50H80N18O16 FW: 1189.3 . fibrinogen

PEPTIDE YY (HUMAN). 0.5mg This peptide has been isolated from human colonic extracts. It is identical in sequence to porcine PYY except for two amino acid replacements. CAS: 118997-30-1 C194H295N55O57 FW: 4309.81 . Synonym: PYY (human)

PEPTIDE YY (HUMAN). 1mg This peptide has been isolated from human colonic extracts. It is identical in sequence to porcine PYY except for two amino acid replacements. CAS: 118997-30-1 C194H295N55O57 FW: 4309.81 . Synonym: PYY (human)

PEPTIDE YY (13-36) (CANINE, MOUSE) 0.5mg This C-terminal fragment was shown to suppress the noradrenaline release from sympathetic nerve endings. It thereby mimics the effects of PYY and NPY at presynaptic (Y2) receptors. The peptide was also able to compete with NPY for essentially all binding sites in rat brain. CAS: 86895-09-2 C135H209N41O38 FW: 3014.4. Synonym: PYY (13-36) (canine, mouse, porcine, rat).

PEPTIDE YY (13-36) (CANINE, MOUSE) 1mg This C-terminal fragment was shown to suppress the noradrenaline release from sympathetic nerve endings. It thereby mimics the effects of PYY and NPY at presynaptic (Y2) receptors. The peptide was also able to compete with NPY for essentially all binding sites in rat brain. CAS: 86895-09-2 C135H209N41O38 FW: 3014.4. Synonym: PYY (13-36) (canine, mouse, porcine, rat).

(DES-PYR1)-LHRH. 5mg CAS: 38280-53-4 C50H70N16O11 FW: 1071.21 . Synonym: (Des-Pyr1)-Gonadorelin

(DES-GLY10,D-ARG6,PRO-NHET9)-LHRH, 5mg Analog of salmon GnRH showing a very high affinity to GnRH receptors used in aquaculture. Usually applied in combination with a dopamine antagonist as domperidone or pimozide, sGnRHa induces ovulation and spawning in a large number of fish species. CAS: 96497-82-4 C64H83N17O12 FW: 1282.47. Synonym: sGnRH-A.

(DES-GLY10,D-ARG6,PRO-NHET9)-LHRH, 25mg Analog of salmon GnRH showing a very high affinity to GnRH receptors used in aquaculture. Usually applied in combination with a dopamine antagonist as domperidone or pimozide, sGnRHa induces ovulation and spawning in a large number of fish species. CAS: 96497-82-4 C64H83N17O12 FW: 1282.47. Synonym: sGnRH-A.

HISTRELIN. 5mg As a potent LHRH agonist, Histrelin stimulates LH and FSH release and inhibits the actions of sex steroids on the male and female reproductive tracts. Its potency in vivo and in vitro is similar to that of the D-Trp6-containing analog. Especially because of its high water solubility and greater lipophilic character, it appears promising for clinical application. CAS: 220810-26-4 C66H86N18O12 FW: 1323.52 . Synonym: Histrelin

ANTIDE. 1mg Antide (Iturelix) is a potent antagonist of GnRH which shows a high antiovulatory activity and releases negligible histamine. CAS: 112568-12-4 C82H108ClN17O14 FW: 1591.32 . Synonym: Iturelix, ORF 23541

ANTIDE. 5mg Antide (Iturelix) is a potent antagonist of GnRH which shows a high antiovulatory activity and releases negligible histamine. CAS: 112568-12-4 C82H108ClN17O14 FW: 1591.32 . Synonym: Iturelix, ORF 23541

KINETENSIN. 5mg This biologically active, neurotensin-related peptide has been obtained by pepsin treatment of human, bovine and dog plasma albumins. Its structure is similar to neurotensin and angiotensin I. Kinetensin increases vascular permeability when injected intradermally into rats and releases histamine from rat mast cells in vitro. CAS: 103131-69-7 C56H85N17O11 FW: 1172.4 . kinetensin

KINETENSIN. 25mg This biologically active, neurotensin-related peptide has been obtained by pepsin treatment of human, bovine and dog plasma albumins. Its structure is similar to neurotensin and angiotensin I. Kinetensin increases vascular permeability when injected intradermally into rats and releases histamine from rat mast cells in vitro. CAS: 103131-69-7 C56H85N17O11 FW: 1172.4 . kinetensin

SYNTIDE 2. 1mg Ca2+ calmodulin-dependent protein kinase II and Ca2+ phospholipid-dependent protein kinase (PKC) were selectively assayed using syntide 2 as substrate. The sequence of syntide 2 is homologous to phosphorylation site 2 in glycogen synthase. CAS: 108334-68-5 C68H122N20O18 FW: 1507.84 . Synonym: Calmodulin-Dependent Protein Kinase Substrate

SYNTIDE 2. 5mg Ca2+ calmodulin-dependent protein kinase II and Ca2+ phospholipid-dependent protein kinase (PKC) were selectively assayed using syntide 2 as substrate. The sequence of syntide 2 is homologous to phosphorylation site 2 in glycogen synthase. CAS: 108334-68-5 C68H122N20O18 FW: 1507.84 . Synonym: Calmodulin-Dependent Protein Kinase Substrate

(D(CH2)51,TYR(ME)2,THR4,ORN8,TYR-) 1mg This oxytocin antagonist shows enhanced affinity for rat uterine oxytocin receptors after iodination. (Disulfide bond) CAS: 114056-26-7 C54H79N11O13S2 FW: 1154.42. Synonym: OVTA.

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