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NF-KB ACTIVATION INHBTR II 5MG - 481408-5MG

GSK-3 INHIBITOR XI CONTRL 1MG - 361556-1MG

PPAR+GAMMA ANTAGONISTIII 50MG - 516566-50MG

AKT INHIBITOR X-5MG - 124020-5MG, 5 mg

STAT3 INHIBITOR PEPTIDE CELL- - 573096-5MG

CHK2 INHIBITOR II-1MG - 220486-1MG

NECROSIS INHIBITOR IM-54-5MG - 480060-5MG

MMP-2 INHIBITOR III 5MG - 444288-5MG

IGF-1R INHIBITOR II +PQ401+-10 - 407248-10MG

IMIQUIMOD-250MG - 401020-250MG

Calbiochem® Phosphatase Inhibitor Cocktail Set III, EMD Millipore - 524627-1ML, 1 ml, Phosphatase inhibitor cocktail set III

Calbiochem® Phosphatase Inhibitor Cocktail Set III, EMD Millipore - 524627-1SET, 1 set, Phosphatase inhibitor cocktail set III

ERK INHIBITOR II NEGATIVE 1MG - 328008-1MG

SHP1/2 PTPASE INHIBITOR NSC-8. 50MG

Ubiquitin Isopeptidase Inhibitor I, G5. Yellow solid. A cell-permeable cross-conjugated a,b-unsaturated dienone compound that induces caspase activation and apoptosis via the apoptosome-independent mitochondrial pathway by selectively inhibiting ubiquitin isopeptidase activity.

Staurosporine, N-Benzoyl. Tan solid. A cell-permeable Staurosporine derivative that displays antitumor properties. Acts as a broad-spectrum, reversible, and ATP-competitive inhibitor of PKC.

TGF-b RI Inhibitor III. A cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of activin receptor-like kinase 4 (IC50 = 129 nM), 5 ( IC50 = 47 nM), and 7. 2mg.

PI 3-Kg Inhibitor II. A cell-permeable thiazolidinedione compound that acts as a potent and ATP-competitive inhibitor of PI 3-Kg. 5mg.

Tubulin Polymerization Inhibitor II. Yellow solid. A cell-permeable, SU5416-derived combretastatin A-4 analog that acts as an effective anti-microtubule agentand displays extremely potent anti-proliferative activity towards various cancer cell lines. 5mg.

Syk Inhibitor IV, BAY 61-3606. Yellow solid. A cell-permeable imidazopyrimidine compound that acts a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src at concentrations as high as 4.7um

PI 3-Ka Inhibitor IV. Off-white solid. A cell-permeable morpholino-thienopyrimidine compound that acts as a potent and isoform-selective inhibitor of PI 3-Ks and inhibits non-PI 3-K kinases only at much higher concentrations. 5mg.

ATM KINASE INHIBITOR 2MG. 2MG

AURORA KINASE CDK INHIBITR 5MG. 5MG

CDK4 INHIBITOR III 5MG. 5MG

CDK/CRK INHIBITOR 1MG. 1MG

CDK2/9 INHIBITOR 5MG. 5MG

IKK INHIBITOR VII 1MG. 1MG

SYK INHIBITOR II 1MG. 1MG

CFTR Inhibitor II, GlyH-101. A cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed and exhibits desirable aqueous solubility. 5mg.

NFAT Activation Inhibitor III. A cell-permeable quinone compound that acts as an inhibitor of Calcineurin-NFAT signaling. Binds to calcineurin with high affinity, disrupts its interaction with NFAT and completely blocks its dephosphorylation, nuclear import of NFAT, and induction of cytokine mRNAs.

1400W. A selective, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd=7nM) both in vitro and in vivo. Has a protective effect against cerebral ischemia. Purity: =95% by HPLC. Soluble in methanol and water. FW: 250.2. 5mg white solid.

D-erythro-Sphingosine, N-Acetyl-. (C2 Ceramide). Biologically active, cell-permeable, non-physiological ceramide analog. Inhibits cell growth and induces apoptosis in HL-60 cells. Purity: =98% by TLC. Soluble in DMSO, ethanol. FW: 341.5. White to off-white solid, 5mg.

Acetyl-Pepstatin. ( [Ac-Val-Val-(3S,4S)-Sta-Ala-(3S,4S)-Sta-OH]). White solid. An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and HIV-2 proteinase (Ki = 5 nM at pH 4.7). Purity: = 97% by HPLC. Soluble in 50% AcOH. CAS 28575-34-0, M.W.

Adenosine 3',5'-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt. Adenosine 3'',5''-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt. (6-Bnz-cAMP, sodium). Lyophilized solid. HYGROSCOPIC. A potent cell-permeable activator of cAMP-dependent protein kinase (PKA).

Protein Kinase A Inhibitor 5-24. ( H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-arg-Arg-Asn-Ala-Ile-His-Asp-OH). Lyophilized solid. HYGROSCOPIC. A potent synthetic peptide inhibitor of PKA (Ki = 2.3 nM). Sequence derived from the heat-stable skeletal muscle inhibitor protein of PKA.

Adenosine 3',5'-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt. Adenosine 3'',5''-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt. (8-CPT-cAMP, sodium). White solid. Cell-permeable cAMP analog that selectively activates protein kinase A.

Adenosine 3',5'-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt. Adenosine 3'',5''-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt. (Rp-8-Br-cAMPS, sodium). Lyophilized solid. HYGROSCOPIC.

Adenosine 3',5'-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt. Adenosine 3'',5''-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt. (Sp-8-Br-cAMPS, sodium). Lyophilized solid. HYGROSCOPIC.

AG 825. ( [4-Hydroxy-3-methoxy-5-(benzothiazolylthiomethyl)benzylidenecyanoacetamide]). Yellow solid. PROTECT FROM LIGHT. A potent and selective inhibitor of HER-2 (neu/erbB-2) (IC50 = 0.35 mM) relative to HER-1 (IC50 = 19 mM) autophosphorylation.

Antithrombin III, Human Plasma. (ATIII; heparin cofactor; Factor Xa inhibitor). Solid lyophilized from 100 mM sodium citrate, 20 mM Tris-HCl, pH 8.3. Single-chain glycoprotein present in normal serum at about 23 mg/100 ml. Principal physiological inhibitor of thrombin.

a2-Antiplasmin, Human Plasma. (a2-Protease inhibitor; primary plasmin inhibitor). Solid lyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4. A 452-amino acid glycoprotein present in plasma at about 70 mg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots.

Autocamtide-2 Related Inhibitory Peptide, Myristoylated. (Myristoylated AIP; H-Myr-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH). Lyophilized solid. HYGROSCOPIC. This peptide corresponds to AIP (Cat. No.

Baicalein. (5,6,7-Trihydroxyflavone). Flavone that inhibits the activity of 12-lipoxygenase (IC50=120nM) and reverse transcriptase. Purity: =98% by TLC. Soluble in acetone and DMSO. CAS: 491-67-8. FW: 270.2. Yellow solid, 10mg.

bpV(phen). ( [Potassium bisperoxo(1,10-phenanthroline)oxovanadate(V)]). Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent insulin receptor kinase (IRK) activator and protein phosphotyrosine phosphatase inhibitor. Excellent insulin mimetic for in vitro and in vivo use (15 mg/kg).

(+)-Brefeldin A, Eupenicillium brefeldianum. ( {1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one}). White solid.

Adenosine 3',5'-cyclic Monophosphate, 8-Bromo-, Sodium. Adenosine 3'',5''-cyclic Monophosphate, 8-Bromo-, Sodium. (8-Bromo-cAMP, sodium). White solid. Cell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP. Preferentially activates protein kinase A.

Butein. 2',4',3,4-Tetrahydroxychalcone; 5mg. Yellow solid. Plant polyphenol acting as protein tyrosine kinase activity inhibitor of EGF receptor & p60c-src. Inhibition is competitive to ATP and non-competitive to substrate. Antioxidant & anti-inflammatory agent. Purity98% HPLC. CAS 487-52-5.

Ca2+/Calmodulin Kinase II Inhibitor 281-309. (CaM kinase II inhibitor 281-309; H-Met-His-Arg-Gln-Glu-Thr-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH). Lyophilized solid. HYGROSCOPIC.

Calpain Inhibitor IV. Potent, cell-permeable, irreversible inhibitor of calpain II (k2=28,900 M-1S-1). Also acts as an inhibitor of cathepsin L (k2=680,000 M-1s-1). Purity: Single spot by TLC. Soluble in DMSO. FW: 557.7. White solid, 1mg.

Calpain Inhibitor V. (Mu-Val-HPh-FMK; Mu-Val-HPh-CH2F). A potent, cell-permeable, and irreversible inhibitor of calpain. Purity: single spot by TLC. Soluble in DMSO. FW: 407.5. Slight brown solid, 1mg.

Calpastatin Peptide. CS Peptide; 500ug; Lyophilized solid. A 27-residue cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC50 = 20 nM for purified rabbit calpain II). Purity 95% HPLC. Supplied as a trifluoroacetate salt.

Calpastatin Peptide. Negative Control; 500ug; White lyophilized solid. HYGROSCOPIC. A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide. Useful as a negative control for Calpastatin Peptide. Purity: 95% by HPLC. Supplied as a trifluoroacetate salt

CAPE. (Caffeic acid phenethyl ester, synthetic). An active component of propolis from honeybee hives. Known to have anti-viral, anti-inflammatory and immunomodulatory properties. HIV-1 integrase inhibitor. Purity: =97% by HPLC. Soluble in DMSO, ethanol. CAS: 104594-70-9. White to beige solid, 25mg.

Caspase Inhibitor II. (Ac-VAD-CHO; Ac-Val-Ala-Asp-CHO). Potent and reversible inhibitor of caspase-1 (ICE), and caspases -3,-4, and -7. Purity: =97% by HPLC. Soluble in DMSO. FW: 329.4. White solid, 1mg.

Caspase Inhibitor I, Biotin Conjugate. (Biotin-VAD-FMK; Biotin-Val-Ala-Asp(OMe)-CH2F). Lyophilized solid. PROTECT FROM MOISTURE. Biotinylated derivative of Caspase-1 Inhibitor V (Cat. No. 627610). Purity: = 80% by TLC. Soluble in DMSO. M.W. 672.8. WARNING! May be carcinogenic/teratogenic.

Caspase-2 Inhibitor I. (Z-VDVAD-FMK; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-CH2F). Lyophilized solid. PROTECT FROM MOISTURE. An irreversible inhibitor of caspase-2 (ICH-1) Purity: = 95% by TLC. Soluble in DMSO. M.W. 695.7.

Caspase-2 Inhibitor I. (Z-VDVAD-FMK; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-CH2F). Lyophilized solid. PROTECT FROM MOISTURE. An irreversible inhibitor of caspase-2 (ICH-1) Purity: = 95% by TLC. Soluble in DMSO. M.W. 695.7.

Caspase Inhibitor III. [Boc-D-FMK; Boc-Asp(OMe)-CH2F]. Cell-permeable, irreversible, broad-spectrum caspase inhibitor. Purity: single spot by TLC. Soluble in DMSO. FW: 263.3. Off-white semi-solid, 1mg.

Caspase Inhibitor III. [Boc-D-FMK; Boc-Asp(OMe)-CH2F]. Cell-permeable, irreversible, broad-spectrum caspase inhibitor. Purity: single spot by TLC. Soluble in DMSO. FW: 263.3. Off-white semi-solid, 250ug.

Caspase-1 Inhibitor VI. Potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE) and caspase-4. Purity: single spot by TLC. Soluble in DMSO. FW: 630.7. White solid, 1mg.

Caspase-1 Inhibitor VI. Potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE) and caspase-4. Purity: single spot by TLC. Soluble in DMSO. FW: 630.7. White solid, 250ug.

Caspase-3 Inhibitor III. (Ac-DEVD-CMK; Ac-Asp-Glu-Val-Asp-CMK). A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspases-6, -7, -8, and -10. Purity: =98% by HPLC. Soluble in DMSO. FW: 551.0. White solid, 1mg.

Caspase-3 Inhibitor III. (Ac-DEVD-CMK; Ac-Asp-Glu-Val-Asp-CMK). A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspases-6, -7, -8, and -10. Purity: =98% by HPLC. Soluble in DMSO. FW: 551.0. White solid, 5mg.

Caspase-5 Inhibitor I. [Z-WEHD-FMK; Z-Trp-Glu(OMe)-His-Asp(OMe)-CH2F]. A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY) as well as caspases-1 and -4. Purity: single spot by TLC. Soluble in DMSO. FW: 763.8. Supplied as a trifluoracetate salt. White solid, 1mg.

Caspase-6 Inhibitor I. (Z-VEID-FMK; Z-Val-Glu(OMe)-Ile-Asp(OMe)-CH2F). An irreversible inhibitor of caspase-6 (Mch-2). Purity: =90% by TLC. Soluble in DMSO. FW: 652.7. Lyophilized solid, 1mg.

Caspase-6 Inhibitor I. (Z-VEID-FMK; Z-Val-Glu(OMe)-Ile-Asp(OMe)-CH2F). An irreversible inhibitor of caspase-6 (Mch-2). Purity: =90% by TLC. Soluble in DMSO. FW: 652.7. Lyophilized solid, 250ug.

Caspase-8 Inhibitor II. [Z-IETD-FMK; Granzyme B Inhibitor III; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F]. A potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Purity: single spot by TLC. Soluble in DMSO. FW: 654.7. White to off-white solid, 1mg.

Caspase-8 Inhibitor II. [Z-IETD-FMK; Granzyme B Inhibitor III; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F]. A potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Purity: single spot by TLC. Soluble in DMSO. FW: 654.7. White to off-white solid, 250ug.

Caspase-4 Inhibitor I, Cell-Permeable. A potent, cell-permeable, and reversible inhibitor of caspase-4 (ICErel-II, TX, ICH-2). Purity: =95% by HPLC. Soluble in DMSO. FW: 1998.5. Supplied as a trifluoroacetate salt. Lyophilized solid, 1mg.

Caspase-6 Inhibitor II, Cell-Permeable. A potent, cell-permeable, and reversible inhibitor of caspase-6 (Mch2). Purity: =95% by HPLC. Soluble in DMSO. FW: 1998.5. Lyophilized solid, 1mg.

Caspase-8 Inhibitor II, Cell-Permeable. A potent, cell-permeable, and reversible inhibitor of caspase-8 (FLICE, MACH, Mch5) and Granzyme B. Purity: =95% by HPLC. Soluble in DMSO. FW: 2000.4. Lyophilized solid, 1mg.

Caspase-9 Inhibitor II, Cell-Permeable. A potent, cell-permeable, and reversible inhibitor of caspase-9 (ICE-LAP6, Mch6). May also inhibit caspase-4 and caspase-5. Purity: =95% by HPLC. Soluble in DMSO. FW: 2036.5. Supplied as a trifluoroacetate salt. Solube in DMSO. Lyophilized solid, 1mg.

Cathepsin B Inhibitor II. ( Ac-Leu-Val-lysinal). White solid. Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) than of leupeptin (IC50 = 310 nM). Purity: = 90% by HPLC. Soluble in H2O. Note: this peptide forms cyclic isomers. M.W. 384.5.

Chelerythrine Chloride. Yellow solid. Naturally occurring alkaloid. Potent, selective cell-permeable inhibitor of protein kinase C (IC50 = 660 nM). Acts on the catalytic domain. Is a competitive inhibitor with respect to the phosphate acceptor and a non-competitive inhibitor with respect to ATP.

Compound 32. ( {AG 1517; 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline; Compound 32}). White solid. PROTECT FROM LIGHT. An extremely potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM; Ki = 6 pM).

Caspase-3 Inhibitor I. A very potent, specific and reversible inhibitor of caspase-3 (IC50=200pM) and caspases -6, -7, -8, and -10. Purity: =90% by HPLC. Soluble in DMSO and water. Sold on basis of peptide content. FW: 502.5. White solid, 1mg.

Caspase-3 Inhibitor I. (CPP32/apopain inhibitor; Ac-DEVD-CHO; Ac-Asp-Glu-Val-Asp-CHO). White solid. A very potent, specific and reversible inhibitor (IC50 = 200 pM) of caspase-3, a member of the ICE/CED-3 family of cysteine proteases. Purity: = 90% by HPLC. Soluble in DMSO and H2O.

Caspase-3 Inhibitor I, Cell-Permeable. A cell-permeable inhibitor of caspase-3, as well as caspases-6, -7, -8, and -10. Purity: =95% by HPLC. Soluble in DMSO. FW: 2000.4. Lyophilized solid, 1mg. Sold on the basis of peptide content.

Daidzein. 25mg white solid. 4' ,7-dihydroxyisoflavone. Packaged under inert gas. Inactive analog of genistein. Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Purity: =98% by TLC. Soluble in DMSO. CAS 486-66-8. M.W. 254.2.

Damnacanthal. (3-Hydroxy-1-methoxyanthraquinone-2-aldehyde). Orange-yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Potent and selective inhibitor of p56lck tyrosine kinase activity.

Caspase-3 Inhibitor II. (Z-DEVD-FMK; Z-Asp(OCH3)-Glu(OCH3)-Val-Asp(OCH3)-FMK). A potent, cell-permeable and irreversible inhibitor of caspases-3, -6, -7, -8, and -10. Purity: single spot by TLC. Soluble in DMSO. FW: 668.7. White solid, 1mg.

Caspase-3 Inhibitor II. (Z-DEVD-FMK; Z-Asp(OCH3)-Glu(OCH3)-Val-Asp(OCH3)-FMK). A potent, cell-permeable and irreversible inhibitor of caspases-3, -6, -7, -8, and -10. Purity: single spot by TLC. Soluble in DMSO. FW: 668.7. White solid, 250ug.

Diphenyleneiodonium Chloride. Irreversible endothelial nitric oxide synthase inhibitor. Inhibits iNOS in macrophages (IC50=50nM). CAS: 4673-26-1. Purity: 97% by TLC. Soluble in DMSO. FW: 314.6. 10mg white solid.

D-erythro-Sphingosine, N,N-Dimethyl-. Clear oil. Inhibits protein kinase C (IC50 = 12 mM) and stimulates src kinase activity. Useful for inhibiting cell surface expression of selectins that promote adhesion of leukocytes or tumor cells to platelets and endothelial cells.

1,2-Dioctanoyl-sn-glycerol. (DOG). Clear colorless liquid. HYGROSCOPIC. PACKAGED UNDER INERT GAS. Cell-permeable activator of protein kinase C (PKC); however, it has lower affinity for PKCa than for other isozymes.

Ebselen. [2-Phenyl-1,2-benzisoselenazol-3(2H)-one; PZ51]. Non-selective inhibitor of the cyclooxygenase activity of prostaglandin H synthase 1 and 2. An excellent scavenger of peroxynitrite. Purity: =98% by TLC. Soluble in DMSO and ethanol. CAS: 60940-34-3. FW: 274.2. Crystalline solid, 5mg.

(-)-Epigallocatechin Gallate. One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties. CAS: 989-51-5. FW: 458.4. Purity: =98% by HPLC. Soluble in water. Light pink solid, 10mg.

EST. ( [E-64d; loxastatin; (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester]). White solid. Membrane-permeable inhibitor of lysosomal cysteine proteases. Similar to E-64 (Cat. No. 324890) but devoid of charged groups.

FeTMPyP. [5,10,15,20-Tetrakis(N-methyl-4'-pyridyl)porphinato iron (III) chloride; FeIIITMPYP(Cl)]. Catalyzes the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-). Prevents oxidation of lipid components by peroxynitrite. Purity: =95% by TLC. Soluble in water. FW: 909.9. Black solid, 10mg.

FPT Inhibitor I. ( {(E,E)-2-[(Dihydroxyphosphinyl)methyl]-3-oxo-3-[(3,7,11-trimethyl-2,6,10-dodecatrienyl)-amino]propanoic acid, sodium}). White solid. HYGROSCOPIC. Potent and selective inhibitor of farnesyltransferase (FTase; IC50 = 83 nM).

FPT Inhibitor II. ( {(E,E)-2-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic acid, sodium}). White solid. HYGROSCOPIC. Potent and selective inhibitor of farnesyltransferase (FTase; IC50 = 75 nM).

FTase Inhibitor I. ( {N-[2(S)-[2(R)-Amino-3-mercaptopropylamino]-3-methylbutyl]-Phe-Met-OH; B581\}). White solid. HYGROSCOPIC. PACKAGED UNDER INERT GAS.

FTI-276. 250ug. Off-white solid. Potent & selective CAAX peptidomimetic of the carboxyl terminal of Ras proteins. Inhibitor of farnesyltransferase in vitro. Inhibits geranylgeranyltransferase I at much higher concentration. Purity: =90% by HPLC. Supplied as a trifluoroacetate salt. MW 433.6.

Genistein. (4' ,5,7-Trihydroxyisoflavone). Inhibits protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50=2.6uM). Purity: =95% by HPLC. Soluble in DMSO. CAS: 446-72-0. FW: 270.2. Yellow crystalline solid, 20mg.

Genistein. (4' ,5,7-Trihydroxyisoflavone). Inhibits protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50=2.6uM). Purity: =95% by HPLC. Soluble in DMSO. CAS: 446-72-0. FW: 270.2. Yellow crystalline solid, 50mg.

GGTI-286. 250 ug. Colorless oil, packaged under inert gas. Selective GGTase I inhibitor. Methyl ester derivative of GGTI-287 is 25-fold more potent than FTI-277 in inhibiting the processing of the geranylgeranylated protein Rap1A. Purity: 85% by HPLC. Supplied as a trifluoroacetate salt

Glyco-SNAP-2. A water-soluble and stable nitric oxide (NO) donor (t1/2=27 hours) with properties similar to those of Glyco-SNAP-1 (80051-924). Dissolve in aqueous buffer immediately after use. Purity: = 96% by NMR. Solubility: methanol and water. FW: 381.4. 5mg green solid.

Go 6983. Red solid. PROTECT FROM LIGHT. A potent inhibitor of protein kinase C (PKC) that has been shown to selectively inhibit several PKC isozymes (IC50 = 7 nM for PKCa and PKCb; 6 nM for PKCg; 10 nM for PKCd and 60 nM for PKCz).

Protein Kinase G Inhibitor. (PKG Inhibitor; H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH). Lyophilized solid. HYGROSCOPIC. A specific inhibitor of PKG (Ki = 86 mM) relative to PKA (Ki = 550 mM). Sequence corresponds to a non-phosphorylatable analog (Ser32 to Ala32) of histone H2B (residues 29 - 35).

Guanosine 3',5'-cyclic Monophosphate, N2,2'-O-Dibutyryl-, Sodium. Guanosine 3'',5''-cyclic Monophosphate, N2,2''-O-Dibutyryl-, Sodium. (Dibutyryl-cGMP, sodium). White solid. Cell-permeable cGMP analog that preferentially activates protein kinase G.

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