Rxreliance

a-Bungarotoxin, Bungarus multicinctus. Lyophilized solid. Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 nM to 1 pM) but does not depress acetylcholine release from motor nerve endings.

ILMAQUINONE 100UG - 401250-100UG

Latrunculin B, Latrunculia magnifica. Yellow solid. A structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes; 10 to 100-fold more potent than cytochalasins. Purity: 98% by TLC. Soluble in DMSO.

Latrunculin A, Latrunculia magnifica. 100ug. White solid, packaged under inert gas. A cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin. Purity:85% by HPLC. CAS 76343-93-6. Protect from light.

SWINHOLIDE A THEONELL 10 UG - 574776-10UG

Brevetoxin PbTx-2, Ptychodiscus brevis. (Brevetoxin B; GbTx-2). Light tan solid. PACKAGED UNDER INERT GAS. Purity: 95% by HPLC. Soluble in EtOAc, MeOH and H2O. RTECS XW5886000, CAS 79580-28-2, M.W. 895.1. WARNING! Toxic. LD50 of = 50 mg/kg.

Brevetoxin PbTx-3, Ptychodiscus brevis. (Pumiliotoxin; dihydrobrevetoxin B). PACKAGED UNDER INERT GAS. Purity: 95% by HPLC. Soluble in EtOAc, MeOH and H2O. RTECS XW5885000, CAS 85079-48-7, M.W. 897.1. WARNING! Toxic. LD50 of = 50 mg/kg.

Diphtheria Toxin, Unnicked, Corynebacterium diphtheriae. Solid lyophilized from sterile 10 mM Tris, 1 mM EDTA, pH 7.5. Catalyzes ADP-ribosylation of eukaryotic aminoacyltransferase II (EF2) using NAD as substrate, thereby inhibiting protein synthesis. May also induce internucleosomal breakdown.

Lipopolysaccharide, E. coli J5. Lyophilized solid, highly purified. Mutant of E. coli O111: B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes. Contaminants: protein: =2.4%; nucleic acid: =0.6%. Soluble in 0.5% TEA. 5mg.

Lipopolysaccharide, Salmonella minnesota Re 595. Lyophilized solid, highly purified. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes. Soluble in 0.5% TEA. 5mg.

Lipopolysaccharide, Salmonella typhimurium. Lyophilized solid, highly purified. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes. Contaminants: protein: =1.5%; nucleic acid: =1.2%. Soluble in water. 5mg.

Tetrodotoxin, Fugu sp.. (TTx). Crystalline solid. Contains sodium citrate. Soluble in H2O. RTECS IO1450000, CAS 4368-28-9, M.W. 319.3. A product of the Fisheries Research Institute of Hebei Province, People'' s Republic of China. WARNING! Toxic. LD50 of = 50 mg/kg.

Lipopolysaccharide, E. coli O111. Lyophilized solid, highly purified. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes. Contaminants: protein: 2.3%; nucleic acid: 1.7%. Soluble in H2O. RTECS OJ0895400. WARNING! Toxic.

Lipid A, Salmonella minnesota Re 595. Lyophilized solid. Prepared by acid hydrolysis of LPS from Salmonella minnesota Re 595. Component responsible for endotoxic properties of gram-negative bacterial lipopolysaccharides.

Pertussis Toxin, Bordetella pertussis. (Islet-activating protein). Solid lyophilized from 50 mM NaCl, 10 mM Na2HPO4, pH 7.0. DO NOT FREEZE. Obtain a uniform suspension before use. A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory protein Gi, Go and Gt.

Tetanus Toxoid, Clostridium tetanii. Solid lyophilized from 10 mM sodium phosphate, pH 7.5. Prepared by formaldehyde inactivation of tetanus toxin. Non-toxic as determined by an LD50 assay in mice.

Tetanus Toxin, Clostridium tetani. 25ug. Lyophilized from 10mM Na phosphate buffer, pH 7.5. Produced by anaerobic bacillus C. tetani. Biological activity: binds GT1b ganglioside in a hemagglutination assay. Purity: single band by SDS-PAGE. Reconstitute with 100 ml H2O. RTECS XW5807000

PERTUSSIS TOXIN IN GLYCROL50UG - 516561-50UG

Pertussis Toxin, Salt-Free, Bordetella pertussis. 50ug. Islet-activating Protein. Lyophilized solid. Catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins. Biological activity =0.01 ng/ml. Five distinct bands on SDS-PAGE. RTECS XW5883750, CAS 70323-44-3. (Not activated).

Jasplakinolide, Jaspis johnstoni. 50ug.Yellow solid. Cell-permeable F-actin probe. Cyclodepsipeptide with antifungal and antitumor properties. Inducer of actin polymerization & stabilization in vitro. Purity=85% by HPLC. CAS 102396-24-7. Protect from light.

ANTHRAX PROTECTIVE ANTIGEN RE - 176905-100UG

LIPOPOLYSACCHARIDE ULTRA PURE - 437628-1MG

ANTHRAX ANTIGEN 100UG - 176908-100UG

CALCITONIN (HUMAN). 1mg Inhibits gastrin and gastric acid secretion. (Disulfide bond) CAS: 21215-62-3 C151H226N40O45S3 FW: 3417.9 . calcitonin

CALCITONIN (HUMAN). 5mg Inhibits gastrin and gastric acid secretion. (Disulfide bond) CAS: 21215-62-3 C151H226N40O45S3 FW: 3417.9 . calcitonin

CALCITONIN (EEL). 1mg (Disulfide bond) CAS: 57014-02-5 C146H241N43O47S2 FW: 3414.91 . calcitonin

CALCITONIN (SALMON I). 1mg Calcitonin inhibits osteoclast activity, lowers the blood calcium level, and positively influences bone mass density. Salmon calcitonin (sCT) is more potent than the human analog.

CALCITONIN (SALMON I). 5mg Calcitonin inhibits osteoclast activity, lowers the blood calcium level, and positively influences bone mass density. Salmon calcitonin (sCT) is more potent than the human analog.

CALCITONIN (SALMON I). 25mg Calcitonin inhibits osteoclast activity, lowers the blood calcium level, and positively influences bone mass density. Salmon calcitonin (sCT) is more potent than the human analog.

A-CGRP (MOUSE, RAT), 0.5mg Induces elevation of cAMP and cGMP in rat aorta. (Disulfide bond) CAS: 83651-90-5 C162H262N50O52S2 FW: 3806.3. CGRP.

A-CGRP (MOUSE, RAT), 1mg Induces elevation of cAMP and cGMP in rat aorta. (Disulfide bond) CAS: 83651-90-5 C162H262N50O52S2 FW: 3806.3. CGRP.

CHYMOSTATIN (MICROBIAL PRODUCT). 5mg The microbial product is a mixture of the chymostatins A, B, and C. It inhibits most cysteine proteases, especially chymotrypsin. Chymostatin is often applied for inhibiting chymase. CAS: 9076-44-2 FW: . chymostatin

CHYMOSTATIN (MICROBIAL PRODUCT). 25mg The microbial product is a mixture of the chymostatins A, B, and C. It inhibits most cysteine proteases, especially chymotrypsin. Chymostatin is often applied for inhibiting chymase. CAS: 9076-44-2 FW: . chymostatin

TYR-PROINSULIN C-PEPTIDE (55-89) . 0.5mg CAS: 139532-11-9 C162H268N50O54 FW: 3780.21 . C Peptide

(SER140)-MYELIN PROTEOLIPID PROTEIN. 1mg This fragment of myelin proteolipid protein is an encephalitogenic determinant, able to bind to diverse sets of T cell receptors. CAS: 122018-58-0 C72H104N20O17 FW: 1521.74 . Synonym: (Ser140)-PLP (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat), (Ser140)-Lipophilin (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)

(SER140)-MYELIN PROTEOLIPID PROTEIN. 5mg This fragment of myelin proteolipid protein is an encephalitogenic determinant, able to bind to diverse sets of T cell receptors. CAS: 122018-58-0 C72H104N20O17 FW: 1521.74 . Synonym: (Ser140)-PLP (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat), (Ser140)-Lipophilin (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)

TSST-1 (58-78). 0.5mg TSST-1 is a superantigen which binds to MHC class II molecules and induces stimulation of T cells. This TSST-1 fragment has an active site of the TSST-1 holotoxin which binds to MHC class II molecules and is able to xenostimulate T cells in an MHC unrestricted manner. Therefore this peptide could be of great value in studying the immunobiology of MHC class II molecules. CAS: 137593-46-5 C98H171N33O35 FW: 2371.64 . toxic shock syndrome

TSST-1 (58-78). 1mg TSST-1 is a superantigen which binds to MHC class II molecules and induces stimulation of T cells. This TSST-1 fragment has an active site of the TSST-1 holotoxin which binds to MHC class II molecules and is able to xenostimulate T cells in an MHC unrestricted manner. Therefore this peptide could be of great value in studying the immunobiology of MHC class II molecules. CAS: 137593-46-5 C98H171N33O35 FW: 2371.64 . toxic shock syndrome

ANGIOTENSIN I/II (1-5). 25mg CAS: 58442-64-1 C30H48N8O9 FW: 664.76 . angiotensin

ANGIOTENSIN I/II (1-5). 100mg CAS: 58442-64-1 C30H48N8O9 FW: 664.76 . angiotensin

(D-ALA7)-ANGIOTENSIN I/II (1-7). 25mg Potent and selective angiotensin (1-7) antagonist. CAS: 159432-28-7 C39H60N12O11 FW: 872.98 . Synonym: A-779

(D-ALA7)-ANGIOTENSIN I/II (1-7). 100mg Potent and selective angiotensin (1-7) antagonist. CAS: 159432-28-7 C39H60N12O11 FW: 872.98 . Synonym: A-779

(CYS18)-ANF (4-18) AMIDE. 0.5mg This ANF analog binds with high affinity to approximately 99% of ANF receptors in the isolated perfused rat kidney. It competes effectively with biologically active atrial peptides for binding sites but is devoid of agonist or antagonist action on the generation of cGMP in vascular smooth muscle and endothelial cells in culture. (Disulfide bond) CAS: 111863-73-1 C64H107N25O19S2 FW: 1594.84 . Synonym: (Des-Gln18,des-Ser19,des-Gly20-+22,des-Leu21)-Atrial Natriuretic Peptide (4-23) amide (mouse, rabbit, rat), C-ANF (4-23)

(CYS18)-ANF (4-18) AMIDE. 1mg This ANF analog binds with high affinity to approximately 99% of ANF receptors in the isolated perfused rat kidney. It competes effectively with biologically active atrial peptides for binding sites but is devoid of agonist or antagonist action on the generation of cGMP in vascular smooth muscle and endothelial cells in culture. (Disulfide bond) CAS: 111863-73-1 C64H107N25O19S2 FW: 1594.84 . Synonym: (Des-Gln18,des-Ser19,des-Gly20-+22,des-Leu21)-Atrial Natriuretic Peptide (4-23) amide (mouse, rabbit, rat), C-ANF (4-23)

CAERULEIN. 1mg This sulfated peptide isolated first from the skin of the Australian frog Litoria caerulea is a more potent secretagogue than its analog CCK-8. Ceruletide is applied in the diagnosis of pancreatic function and, in high dosage, for the induction of pancreatitis in experimental animals. CAS: 17650-98-5 C58H73N13O21S2 FW: 1352.42 . Synonym: Ceruletide, Cerulein

CAERULEIN. 5mg This sulfated peptide isolated first from the skin of the Australian frog Litoria caerulea is a more potent secretagogue than its analog CCK-8. Ceruletide is applied in the diagnosis of pancreatic function and, in high dosage, for the induction of pancreatitis in experimental animals. CAS: 17650-98-5 C58H73N13O21S2 FW: 1352.42 . Synonym: Ceruletide, Cerulein

HYMENISTATIN I. 1mg Hymenistatin I (HS-I) exerts an immunosuppressive effect in the humoral and cellular immune responses comparable with that of cyclosporin A (CsA). Comparison of the influence of HS-I and CsA on cytokine production sug gests that the mechanisms of the interaction with the immunological system are substantially different for the two compounds tested. CAS: 129536-23-8 C47H72N8O9 FW: 893.14 . Synonym: HS-I

HYMENISTATIN I. 5mg Hymenistatin I (HS-I) exerts an immunosuppressive effect in the humoral and cellular immune responses comparable with that of cyclosporin A (CsA). Comparison of the influence of HS-I and CsA on cytokine production sug gests that the mechanisms of the interaction with the immunological system are substantially different for the two compounds tested. CAS: 129536-23-8 C47H72N8O9 FW: 893.14 . Synonym: HS-I

SOMATOSTATIN-14 (REDUCED). 1mg C76H106N18O19S2 FW: 1639.92 . somatostatin

(D-PHE7)-SOMATOSTATIN-14. 1mg (Disulfide bond) CAS: 64813-74-7 C76H104N18O19S2 FW: 1637.91 . somatostatin

SOMATOSTATIN-14 (3-14). 1mg (Disulfide bond) CAS: 54518-51-3 C71H96N16O17S2 FW: 1509.77 . somatostatin

DENDROASPIS NATRIURETIC PEPTIDE. 0.5mg This 38 amino acid peptide, which has been originally isolated from the venom of the green mamba snake (Dendroaspis angusticeps), shares structural homology with the family of natriuretic peptides. It contains a 17 amino acid disulfide ring similar to ANP, BNP, and CNP, which mediate biological actions throug h particulate guanylyl cyclase receptors and generation of guanosine monophosphate (cGMP). (Disulfide bond) CAS: 255721-52-9 C180H282N56O56S2 FW: 4190.69 . Synonym: DNP

SOMATOSTATIN-28. 0.5mg This octacosapeptide S-28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a larger precursor, preprosomatostatin. S-28 was first isolated from porcine duodenum. In guinea-pig pancreatic acini, S-28, unlike S-14, increased amylase secretion, cellular cyclic GMP, and Ca2+ outfluxes. (Disulfide bond) CAS: 73032-94-7 C137H207N41O39S3 FW: 3148.6 . somatostatin

SOMATOSTATIN-28. 1mg This octacosapeptide S-28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a larger precursor, preprosomatostatin. S-28 was first isolated from porcine duodenum. In guinea-pig pancreatic acini, S-28, unlike S-14, increased amylase secretion, cellular cyclic GMP, and Ca2+ outfluxes. (Disulfide bond) CAS: 73032-94-7 C137H207N41O39S3 FW: 3148.6 . somatostatin

TYR-SOMATOSTATIN-14. 1mg (Disulfide bond) CAS: 58100-03-1 C85H113N19O21S2 FW: 1801.08

(TYR1)-SOMATOSTATIN-14. 1mg (Disulfide bond) CAS: 59481-23-1 C82H108N18O20S2 FW: 1730 . somatostatin

ANGIOTENSIN I (1-9). 25mg Angiotensin I (1-9) is found in vivo and accumulates in animals treated with ACE inhibitors. It has been shown that the nonapeptide may be generated in heart and kidney by endothelium-associated ACE2. Kramkowski et al. observed that DRVYIHPFH generated from Ang I in platelets enhances thrombosis in rats. CAS: 34273-12-6 C56H78N16O13 FW: 1183.34 . angiotensin

ANGIOTENSIN I (1-9). 100mg Angiotensin I (1-9) is found in vivo and accumulates in animals treated with ACE inhibitors. It has been shown that the nonapeptide may be generated in heart and kidney by endothelium-associated ACE2. Kramkowski et al. observed that DRVYIHPFH generated from Ang I in platelets enhances thrombosis in rats. CAS: 34273-12-6 C56H78N16O13 FW: 1183.34 . angiotensin

PREPRO-ANF (26-55) (HUMAN). 0.5mg Prepro-atrial natriuretic factor (26-55) (human) is one of four peptide hormones derived from the atrial natriuretic prohormone. It is also known as long acting natriuretic peptide. The peptide has potent vasodilatory properties equal to atrial natriuretic factor. Vasodilation is associated with a 4-5 fold increase in cyclic GMP levels due to activation of particulate guanylate cyclase activity. Like prepro-atrial natriuretic factor (56-92) and kaliuretic peptide it is present in higher concentration in individuals with congestive heart failure. It causes the maximal increase in prostaglandin E2 (PGE2) levels of the three peptides. The known increase in PGE2 in chronic heart failure may be in part secondary to these peptides. CAS: 112160-82-4 C152H236N3....

PREPRO-ANF (26-55) (HUMAN). 0.5mg CAS: 112199-06-1 C173H270N44O57 FW: 3878.31 . Synonym: Prepro-hANF (56-92) (human)

(N-ME-D-TRP4,THR8)-OCTREOTIDE AMIDE, 1mg This synthetic somatostatin analog is selective for the human somatostatin receptor subtype 5 (hsst5) with a binding affinity similar to somatostatin-28. Its Kd +/-SEM values for hsst1, hsst2, hsst3, hsst4, and hsst5 are 1200 nM, 23.5 +/- 3.92 nM, 11.05 +/- 1.03 nM, 1000 nM, and 0.61 +/- 0.36 nM, respectively. Due to its selectivity it might prove to be useful for evaluating hsst5-mediated responses. (Disulfide bond) CAS: 340821-13-8 C50H67N11O10S2 FW: 1046.28. Synonym: (N-Me-D-Trp4,Thr8)-Octreotide amide, (N-Me-D-Trp4)-Octreotate amide.

(ASN1, VAL5)-ANGIOTENSIN II, 25mg. CAS: 53-73-6 C49H70N14O11 FW: 1031.18. Synonym: Angiotensinamide.

ANGIOTENSIN I/II (3-7). 25mg CAS: 122483-84-5 C31H45N7O7 FW: 627.74 . angiotensin

ANGIOTENSIN I/II (3-8). 25mg Ang IV, one of the major metabolites of angiotensin II, binds with high affinity to a new angiotensin binding site distinct and separate from angiotensin II receptors. CAS: 23025-68-5 C40H54N8O8 FW: 774.92 . Synonym: Angiotensin IV

ANGIOTENSIN I/II (3-8). 100mg Ang IV, one of the major metabolites of angiotensin II, binds with high affinity to a new angiotensin binding site distinct and separate from angiotensin II receptors. CAS: 23025-68-5 C40H54N8O8 FW: 774.92 . Synonym: Angiotensin IV

C-TYPE NATRIURETIC PEPTIDE (1-53). 1mg (Disulfide bond) CAS: 141294-77-1 C251H417N81O71S3 FW: 5801.77 . Synonym: CNP-53 (human)

ANGIOTENSIN II RECEPTOR LIGAND. 1mg Depending on concentrations this peptide acts as a selective agonist or antagonist of AT2 receptor-mediated effects. CAS: 127060-75-7 C52H69N13O11 FW: 1052.2 . Synonym: CGP42112, CGP42112A

ANGIOTENSIN II RECEPTOR LIGAND. 5mg Depending on concentrations this peptide acts as a selective agonist or antagonist of AT2 receptor-mediated effects. CAS: 127060-75-7 C52H69N13O11 FW: 1052.2 . Synonym: CGP42112, CGP42112A

H-Arg-Val-Leu-(-)-Phe-Glu-Ala-Nle-NH2.