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Actinomycin D is a nonfluorescent GC-selective interculator, actinomycin D has also been used for chromosome banding studies. Orange red solid soluble in DMSO at 50 mg/mL, Store at 4 Deg C, C62H86N12O16, 10MG

Dapi Dilactate. is essentially the same as dapi (dihydrochloride) (40011) except for the difference in their counter ions. the dilactate counter ions make the dye more water soluble and therefore dapi dilactate is a better choice if one wants to make the stock solution in deionized water.

Ethidium Homodimer I. a high affinity fluorescent nucleic acid stain that binds to dna and rna with a 30-fold fluorescence enhancement. the dye is highly positive charged and cell-impermeable but it is very useful to detect nucleic acids in solution or cells with a disintegrated cell membrane.

Dapi. is a popular blue fluorescent dna probe. the dye binds to the minor groove of dsdna with a -20-fold fluorescence enhancement. dapi is also used as a common nuclear counterstain in microscopy.

Dmao. is a membrane-permeable dna dye. the dye preferentially binds to dsdna with green fluorescence. the dye is excellent for staining live bacteria. unlike sybr dyes, dmao is extremely stable

PMA. High affinity photoreactive DNA binding dye that is cell impermeable but can be selectively used to modify DNA from dead cells

Ethidium Homodimer I (40010). is supplied in a ready-to-use format.

Ethidium Monoazide. a fluorescent photoafinity label that, after photolysis, binds covalently to nucleic acids both in solution and in cells that have compromised membranes. the fluorescence of ethidium monoazide is weak, but the intensity - moreincreases -15-fold on binding to dna

Propidium Iodide. Nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population, and as a counterstain in multicolor fluorescent imaging

Propidium iodide (40016). Supplied in a ready to use form.

5-Aminoallyl-dUTP can be enzymatically incorporated into DNA. The resulting amine-containing DNA can be subsequently labeled with a fluorescent dye, biotin or other haptens. This two-step method for labeling nucleic acids is more economical than the one-step method using a prelabeled dUTP.

5-Aminoallyl-dUTP, lyophilized. 5-Aminoallyl-dUTP (40020) is in a lyophilized powder form that is suitable for long term storage.

5-Aminoallyl-UTP, 10 mM. 5-Aminoallyl-UTP can be enzymatically incorporated into DNA. The resulting amine-containing DNA can be subsequently labeled with a fluorescent dye, biotin or other haptens via conventional peptide coupling method.

5-Aminoallyl-UTP, lyophilized . 5-Aminoallyl-UTP (40021) is in a lyophilized powder form that is suitable for long term storage.

Biotin-16-dUTP, Biotium - 40022, 50 µl (1 mM solution), Biotin-16-dUTP 1 mM in pH 7.5 Tris-HCl buffer

Biotin-16-dUTP, lyophilized. Biotin-16-dUTP (40022) is in a lyophilizes solid that is suitable for long term storage.

Biotin-16-UTP, 10 mM. Biotin-16-UTP can be enzymatically incorporated into RNA via nick translation, random priming, or 3G-end terminal labeling. The long 16 atoms linker allows better interaction of biotin with avidin or streptavidin.

5-BROMO-2-DEOXYURIDINE - 40024, 100 mg

5-BrdUTP, 10 mM in TE buffer. 5-Bromo-dUTP is widely used in TUNEL assay to detect apoptosis cells, and it is also a good substrate for reverse transcriptase.

5-BrUTP, 10 mM. BrUTP can be enzymatically incorporated into RNA

Biotin-11-dUTP, Biotium - 40029, 50 µl, Biotin-11-dUTP 1 mM in pH 7.5 Tris-HCl buffer

Biotin-11-dUTP, lyophilized. Biotin-11-dUTP (40029) is in a lyophilized powder form that is suitable for long term storage.

Biotin-20-dUTP, Biotium - 40030, 50 µl (1 mM solution), Biotin-20-dUTP 1 mM in pH 7.5 Tris-HCl buffer

Biotin-20-dUTP, lyophilized. Biotin-20-dUTP (40030) is in a lyophilized powder form that is suitable for long term storage.

Biotin-11-UTP, 10 mM. Biotin-11-UTP can be enzymatically incorporated into RNA.

Biotin-20-UTP. is similar to biotin-11-UTP (40033) and biotin-16-UTP (40023) except that it has a longer and water soluble spacer group, which should facilitate interaction between the biotin group and avidin or streptavidin.

Biotin-11-Dctp. 1mm biotin-11-dctp can be enzymatically incorporated into dna via nick translation, random priming, or 3'-end terminal labeling. the number 11 is the number of atoms in the linker between biotin and dctp.

7-Aad. is a fluorescent dna intercalator, which upon binding to dsdna can be excited by the argon-ion laser and emits at 647 nm. 7-aad binds selectively to gc regions of dna, which makes the dye useful for chromosome banding studies.

Acridine Orange (Ao). stains dsdna green (525 nm) and rna or single stranded dna red (650 nm). the dye is cell permeable and its nucleic acid binding property has been used for cell-cycle studies. acridine orange has been used for the detction of microorganisms in cerebrospinal fluid.

Dodc. has been reported to bind to triplex dna, as well as dimeric hairpin quadruplex dna. binding of the dye to triplex dna quenches the fluorescence of the dye and red-shifts the dye absorption peak.

Disc2(5). binds to dna-dna or pna-dna duplexes with a large blue-shift of the absorption spectrum. binding of the dye to pna-dna hybrid, in particular, blue-shifts the dye absorption spectrum by as much as 115 nm, offering a visual method to detect nucleic acid hybridization.

Ethidium Bromide (Eb). is a popular nucleic acid gel stain. the dye binds to dna with 10-fold fluorescence enhancement and has little sequence preference. eb is a potent mutagen, biotium offer eb in h2o as a safer alternative to the more hazardous powdery form.

DAPI, 10mg/mL In H2O.

Hoechst 33258 (40045). biotium offers hoechst 33258 (40045) in aqueous solution for safe and easy handling.

Hoechst dyes. Cell membrane-permeant, minor groove-binding blue fluorescent DNA stains. Hoechst dye are widely used in cell cycle and apoptosis studies and also as nuclear counterstains.

Hoechst 33342 (40047). biotium offers hoechst 33342 (40047) in aqueous solution for safe and easy handling.

Hoechst dyes. Cell permeable,minor groove-binding blue fluorescent DNA stains. Hoechst dye are widely used in cell cycle and apoptosis studies and also as nuclear counterstains

Ethidium Homodimer Iii. was developed by biotium as an alternative to ethidium homodimer i. it has an absorption and emission spectra similar to those of ethidium homodimer i. however, the dye stains dna 70% brighter than ethidium homodimer i.

Ethidium Homodimer Iii (40050). is supplied in a ready to use form.

SIRT1/2 INHIBITOR VIII - 566330-10MG

OSTEOSTATIN (1-5) AMIDE (HUMAN. 25mg This pTHrP fragment stimulated membrane-associated protein kinase C in freshly isolated rat spleen lymphocytes and thus raises the possibility of being a physiological regulator of the proliferation and other activities of lymphocytes. CAS: 155918-12-0 C27H42N10O7 FW: 618.69 . Synonym: pTH-Related Protein (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), pTH-rP (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), Hypercalcemia of Malignancy Factor (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat)

(D-LYS3)-GHRP-6. 5mg A ghrelin receptor antagonist, as well as of GHRP-6 (H-9990). Asakawa et al. found that peripherally administered (D-Lys-)-GHRP-6 decreased food intake in lean mice, in mice with diet induced obesity, and in ob/ob obese mice, and that repeated administration of this GHS-R antagonist decreased body weight gain and improved glycaemic control in ob/ob obese mice. CAS: 136054-22-3 C49H63N13O6 FW: 930.12 . Synonym: (D-Trp7,D-Lys8,D-Phe10)-a-MSH (6-11) amide, (D-Lys3)-Growth Hormone-Releasing Peptide-6

(D-LYS3)-GHRP-6. 25mg A ghrelin receptor antagonist, as well as of GHRP-6 (H-9990). Asakawa et al. found that peripherally administered (D-Lys-)-GHRP-6 decreased food intake in lean mice, in mice with diet induced obesity, and in ob/ob obese mice, and that repeated administration of this GHS-R antagonist decreased body weight gain and improved glycaemic control in ob/ob obese mice. CAS: 136054-22-3 C49H63N13O6 FW: 930.12 . Synonym: (D-Trp7,D-Lys8,D-Phe10)-a-MSH (6-11) amide, (D-Lys3)-Growth Hormone-Releasing Peptide-7

GASTRIN TETRAPEPTIDE. 100mg Tetragastrin seems to be a potent releaser of insulin and other islet hormones. CAS: 1947-37-1 C29H36N6O6S FW: 596.71 . Synonym: Gastrin (14-17) (human), Cholecystokinin Tetrapeptide, CCK-4, Cholecystokinin Octapeptide (5-8), Tetragastrin

HUMAN GROWTH HORMONE (1-43). 0.5mg This insulin-potentiating hGH-fragment has been detected in human serum. Treatment of obese yellow Avy/A mice with hGH (1-43) enhanced the in vitro sensitivity of their adipose tissue to insulin. CAS: 96827-07-5 C240H358N62O67S FW: 5215.93 . Synonym: hGH (1-43), Somatotropin (1-43) (human)

HUMAN GROWTH HORMONE (1-43). 1mg This insulin-potentiating hGH-fragment has been detected in human serum. Treatment of obese yellow Avy/A mice with hGH (1-43) enhanced the in vitro sensitivity of their adipose tissue to insulin. CAS: 96827-07-5 C240H358N62O67S FW: 5215.93 . Synonym: hGH (1-43), Somatotropin (1-43) (human)

REC HUMAN GROWTH HORMONE. 0.5mg Fully active in biological assays when compared to known standards. Endotoxin level 0.1 ng per -g hGH. FW: . Synonym: rec hGH

REC HUMAN GROWTH HORMONE. 1mg Fully active in biological assays when compared to known standards. Endotoxin level 0.1 ng per -g hGH. FW: . Synonym: rec hGH

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