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FETAL BOVINE SERUM DEFINED NZ 50ML - SH31194.01

FETAL BOVINE SERUM DEFINED NZ HI 50ML - SH31194.01HI

FETAL BOVINE SERUM DEFINED NZ 100ML - SH31194.02

FETAL BOVINE SERUM DEFINED NZ HI 100ML - SH31194.02HI

FETAL BOVINE SERUM DEFINED NZ 500ML - SH31194.03

FETAL BOVINE SERUM DEFINED NZ HI500ML - SH31194.03HI

FETAL BOVINE SERUM DEFINED NZ IR 500ML - SH31194.03IR25-40

FETAL BOVINE SERUM DEFINED NZ 500ML. - SH31194.03IR30-45

FETAL BOVINE SERUM DEFINED AU HI50ML - SH31195.01HI

FETAL BOVINE SERUM DEFINED AU 100ML - SH31195.02

FETAL BOVINE SERUM DEFINED AU HI 100ML - SH31195.02HI

FETAL BOVINE SERUM DEFINED AU 500ML - SH31195.03

FETAL BOVINE SERUM DEFINED AU HI 500ML - SH31195.03HI

FETAL BOVINE SERUM DEFINED AU IR 500ML - SH31195.03IR25-40

FETAL BOVINE SERUM DEFINED AU 500ML. - SH31195.03IR30-45

MGLUR5 ANTAGONIST MTEP-5MG - 445874-5MG

NG-Hydroxy-L-arginine, Monoacetate. Key intermediate in biosynthesis of nitric oxide by constitutive nitric oxide synthase (cNOS). NOHA can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450. CAS: 53598-01-9. FW: 250.3. Purity: 98% by TLC. Soluble in water. 5mg white solid.

L-N5-(1-Iminoethyl)ornithine, Dihydrochloride. Approximately five times more potent as an inhibitor of endothelial cell nitric oxide synthase (IC50=500nM) than other arginine analogs such as L-NAME and L-NMMA. Purity: =98% by TLC. Soluble in water. 20mg white solid. FW: 246.1.

Carbachol. (Carbamoylcholine chloride). White solid. HYGROSCOPIC. An unsubstituted carbamoyl ester that acts as an agonist for nicotinic and muscarinic acetylcholine receptors. Carbachol is totally resistant to the action of acetylcholine esterase (AChE) and non-specific cholinesterases.

L-(- )-Epinephrine-(+)-bitartrate. ( [Adrenaline; 1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanol]). White solid. HYGROSCOPIC. a,b-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP.

(- )-Nicotine, Ditartrate. ( [(S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, di-d-tartrate] ). White solid. Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions. Purity: = 95% by HPLC. Soluble in EtOH and H2O.

L-(-)-NOREPINEPHRINE-( 100MG - 489350-100MG

Picrotoxin, Anamirta cocculin. White solid. A potent antagonist of GABA receptors (IC50 = 240 nM) at synapses in the central nervous system. Inhibits 35S-TBPS binding to the Cl- channel (IC50 = 1.7 mM). Picrotoxin is a mixture of one mole of picrotoxinin and one mole of picrotin.

D-(G)-2-Amino-5-phosphonopentanoic Acid. 5mg. D-AP5. White solid. Hygroscopic. Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Purity:97% by HPLC. CAS 79055-68-8.

Histamine, Free Base. [2-(4-Imidazolyl)ethylamine]. Potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Purity: 99% by TLC. Soluble in water. CAS: 51-45-6. FW: 111.2. Off-white solid, 1g.

Histamine, Free Base. [2-(4-Imidazolyl)ethylamine]. Potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Purity: 99% by TLC. Soluble in water. CAS: 51-45-6. FW: 111.2. Off-white solid, 5g.

Nimodipine. ( [1,4-Dihydro-2,6-dimethyl-4-(3'' -nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl-1-methylethyl ester]). Off-white solid. PROTECT FROM LIGHT. An L-type Ca2+ channel blocker. Enhances memory in old or brain-damaged animals.

Isoproterenol, HCl. White solid. PROTECT FROM LIGHT. Phenethylamine derivative. Selective b-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation.

N-Methyl-D-aspartic Acid. (NMDA). White solid. Excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy.

[beta]-Amyloid Peptide (1-42), Human. Region: Corresponds to amino acids 1-42 of the processed human amyloid peptide. Purity: 95% by HPLC. Applications: Neurotoxicity studies, substrate cleavage assay. Lyophilized 250ug.

IBERITOTOXIN BUTHUS TAMULUS R - 401002-10UG

Kainic Acid. 10mg. 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid. White solid. An excitatory amino acid receptor agonist selective for the kainate receptor subtype. Also activates AMPA receptors. Purity: =98% by HPLC. RTECS UX9665250, CAS 487-79-6. MW 213.2.

FLUOXETINE HYDROCHLORIDE-25MG - 343290-25MG

CARBOXY-PTIO SODIUM SALT-10MG - 217386-10MG

P75NTR SIGNALING INHIBITOR CE - 506181-500UG

MGLUR5 LIGAND CDPPB-1MG. 5MG

Inhibitor E-4031 5Mg. 4'-[[1-[2-(6-Methyl-2-pyridinyl)ethyl-4-piperidinyl]carbonyl]methanesulfonanilide, 2HCl Form Solid Cas number 113558-89-7 Purity G98% by TLC.A specific blocker of HERG channels (IC50 = 7.7 nM).

B-Secretase Activity Assay Kit.

STICHODACTYLA HELIANTHUS NEUROTOX. 0.5mg ShK-toxin, originally isolated from the sea anemone Stichodactyla helianthus, has been found to inhibit the specific binding of dendrotoxin I to rat brain membranes. Due to its unique structure (it contains three intramolecular disulfide bridges) and high affinity for some potassium channels, ShK-toxin may become a useful molecular probe for investigating potassium channels. (Disulfide bonds between Cys3 and Cys35/Cys12 and Cys28/Cys17 and Cys32) CAS: 172450-46-3 C169H274N54O48S7 FW: 4054.83 . Synonym: ShK

STICHODACTYLA HELIANTHUS NEUROTOX. 1mg ShK-toxin, originally isolated from the sea anemone Stichodactyla helianthus, has been found to inhibit the specific binding of dendrotoxin I to rat brain membranes. Due to its unique structure (it contains three intramolecular disulfide bridges) and high affinity for some potassium channels, ShK-toxin may become a useful molecular probe for investigating potassium channels. (Disulfide bonds between Cys3 and Cys35/Cys12 and Cys28/Cys17 and Cys32) CAS: 172450-46-3 C169H274N54O48S7 FW: 4054.83 . Synonym: ShK

DYNORPHIN A. 1mg Licensed from Eisai Co., Ltd. for sale for noncommercial research use only (US Pat. 4,481,138, EP 0 070 569). CAS: 80448-90-4 C99H155N31O23 FW: 2147.52 . Synonym: Prodynorphin (207-223) (human), Prodynorphin (209-225) (porcine)

DYNORPHIN A. 5mg Licensed from Eisai Co., Ltd. for sale for noncommercial research use only (US Pat. 4,481,138, EP 0 070 569). CAS: 80448-90-4 C99H155N31O23 FW: 2147.52 . Synonym: Prodynorphin (207-223) (human), Prodynorphin (209-225) (porcine)

DYNORPHIN A (1-13). 1mg Endogenous kappa-opioid receptor agonist. It is sug gested that it attenuates galanin-induced impairment of memory processes throug h the mediation of kappa-opioid receptors. CAS: 72957-38-1 C75H126N24O15 FW: 1603.98 . dynorphin

DYNORPHIN A (1-13). 5mg Endogenous kappa-opioid receptor agonist. It is sug gested that it attenuates galanin-induced impairment of memory processes throug h the mediation of kappa-opioid receptors. CAS: 72957-38-1 C75H126N24O15 FW: 1603.98 . dynorphin

DYNORPHIN A (1-8). 5mg CAS: 75790-53-3 C46H72N14O10 FW: 981.17 . dynorphin

DYNORPHIN A (1-8). 25mg CAS: 75790-53-3 C46H72N14O10 FW: 981.17 . dynorphin

DYNORPHIN B. 1mg CAS: 83335-41-5 C74H115N21O17 FW: 1570.86 . Synonym: Rimorphin, Prodynorphin (226-238) (human), Prodynorphin (228-240) (porcine)

DYNORPHIN B. 5mg CAS: 83335-41-5 C74H115N21O17 FW: 1570.86 . Synonym: Rimorphin, Prodynorphin (226-238) (human), Prodynorphin (228-240) (porcine)

CRF (BOVINE). 0.5mg CAS: 92307-52-3 C206H340N60O63S FW: 4697.4 . Synonym: Corticotropin-Releasing Factor (bovine)

CRF (BOVINE). 1mg CAS: 92307-52-3 C206H340N60O63S FW: 4697.4 . Synonym: Corticotropin-Releasing Factor (bovine)

(D-PHE12,NLE21-+38,A-ME-LEU37)-CRF, 0.5mg Potent and long-acting CRF antagonist. CAS: 150646-45-0 C159H267N49O43 FW: 3553.17. CRF.

(D-PHE12,NLE21-+38,A-ME-LEU37)-CRF, 1mg Potent and long-acting CRF antagonist. CAS: 150646-45-0 C159H267N49O43 FW: 3553.17. CRF.

ASTRESSIN. 0.5mg The Glu30 to Lys33 lactam bridge constrains astressin in an +-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than +-helical CRF (9-41) (H-2040) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date. CAS: 170809-51-5 C161H269N49O42 FW: 3563.24 . Synonym: (D-Phe12,Nle21-+38,Glu30,Lys33)-CRF (12-41) (human, rat)

ASTRESSIN. 1mg The Glu30 to Lys33 lactam bridge constrains astressin in an +-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than +-helical CRF (9-41) (H-2040) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date. CAS: 170809-51-5 C161H269N49O42 FW: 3563.24 . Synonym: (D-Phe12,Nle21-+38,Glu30,Lys33)-CRF (12-41) (human, rat)

CRF (6-33) (HUMAN, RAT), 0.5mg This CRF fragment may have two different beneficial effects in Alzheimer's disease (AD). First CRF (6-33) dissociates CRF from the CRF-binding protein and may therefore be able to restore the dramatic reduction of free CRF content in AD. Second this fragment shows cognition-enhancing properties in animal models of learning and memory, without the characteristic anxiogenic effects of CRF receptor agonists, and may therefore be useful in the treatment of memory deficits seen in AD. CAS: 120066-38-8 C141H231N41O43S FW: 3220.7. CRF.

CRF (6-33) (HUMAN, RAT), 1mg This CRF fragment may have two different beneficial effects in Alzheimer's disease (AD). First CRF (6-33) dissociates CRF from the CRF-binding protein and may therefore be able to restore the dramatic reduction of free CRF content in AD. Second this fragment shows cognition-enhancing properties in animal models of learning and memory, without the characteristic anxiogenic effects of CRF receptor agonists, and may therefore be useful in the treatment of memory deficits seen in AD. CAS: 120066-38-8 C141H231N41O43S FW: 3220.7. CRF.

Z-Val-Asp(OMe)-Val-Ala-DL-Asp(OMe)-fluoromethylketone. Z-VD(OMe)VAD(OMe)-FMK.

Antazoline.0.5H2SO42-(N-Phenyl-N-benzyl-aminomethyl)-imidazoline.0.5H2SO4. Benzyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl-amine . 0.5 H2SO4.

Antazoline.0.5H2SO42-(N-Phenyl-N-benzyl-aminomethyl)-imidazoline.0.5H2SO4. Benzyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl-amine . 0.5 H2SO4.

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